Pemetrexed

Hazard statements (CLP)

H315, H341, H360FD, H372

Code

Statements

H315

Causes skin irritation

SECTION 2: Hazards identification

Labelling according Regulation (EC) No 1272/2008 as amended by GB-CLP Classification of the substance or mixture

Signal word

Danger Danger

Hazard statements

H315 Causes skin irritation. H341 Suspected of causing genetic defects. H360FD May damage fertility. May damage the unborn child. H372 Causes damage to organs (Blood, Immune system, Testes) through prolonged or repeated exposure. H341 Suspected of causing genetic defects. H372 Causes damage to organs through prolonged or repeated exposure. H360FD May damage fertility. May damage the unborn child.

Precautionary statements

P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust. P264 Wash skin thoroughly after handling. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P302 + P352 IF ON SKIN: Wash with plenty of water. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust. P264 Wash skin thoroughly after handling. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 IF exposed or concerned: Get medical advice/ attention.

Supplemental label elements

none Reduced Labelling (<= 125 ml) none

Other hazards

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher

ECOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

TOXICOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

2.1 Classification of the substance or mixture

Classification according to Regulation (EC) No 1272/2008 as amended by GB-CLP Regulation, UK SI 2019/720, and UK SI 2020/1567 Skin irritation, (Category 2) H315: Causes skin irritation. Germ cell mutagenicity, H341: Suspected of causing genetic (Category 2) defects. Reproductive toxicity, (Category H360FD: May damage fertility. May 1A) damage the unborn child. Specific target organ toxicity - H372: Causes damage to organs through repeated exposure, (Category 1), prolonged or repeated exposure. Blood, Immune system, Testes