(−)-Nicotine

Sigma-Aldrich Inc

Revision date : 2025-12-24

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GHS06 GHS05 GHS09
Health risk rating 5
Safety risk rating 1
Environmental risk rating 4

Note: Ingredients listed on restricted chemical lists

EC/CAS

200-193-3/54-11-5

Name of the chemical

Nicotine and its salts

Concentration

>=90-<=100

General Information

Version

7.11

Revision date

2025-12-24

Product name

(−)-Nicotine

CAS No.

54-11-5

REACH No

A

Emergency telephone

800-424-9300, +1-703- 527-3887

Icons in SDS

GHS05 GHS06 GHS09 M004 M009 M017

Company Information

company name

Sigma-Aldrich Inc

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H300, H300+H310+H330, H310, H315, H318, H330, H411

Hazard statements

Code

Statements

H300

Fatal if swallowed

Section 2

SECTION 2: Hazards identification

Regulation (EC) No. 1272/2008 Classification of the substance or mixture

Signal word

Danger Danger

Hazard statements

H300 + H310 + H330 Fatal if swallowed, in contact with skin or if inhaled. H315 Causes skin irritation. H318 Causes serious eye damage. H411 Toxic to aquatic life with long lasting effects. H318 Causes serious eye damage. H300 + H310 + H330 Fatal if swallowed, in contact with skin or if inhaled.

Precautionary statements

P262 Do not get in eyes, on skin, or on clothing. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P262 Do not get in eyes, on skin, or on clothing. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P302 + P352 + P310 IF ON SKIN: Wash with plenty of water. Immediately call a POISON CENTER/ doctor. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Response

P302 + P352 + P310 IF ON SKIN: Wash with plenty of water. Immediately call a POISON CENTER/ doctor. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Reduced Labelling (<= 125 ml)

Supplemental label elements

none

2.3 Other hazards

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

ECOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

TOXICOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

2.1 Classification of the substance or mixture

Classification (REGULATION (EC) No 1272/2008) Acute toxicity, Category 1 H300: Fatal if swallowed. Acute toxicity, Category 2 H330: Fatal if inhaled. Acute toxicity, Category 2 H310: Fatal in contact with skin. Skin irritation, Category 2 H315: Causes skin irritation. Serious eye damage, Category 1 H318: Causes serious eye damage. Long-term (chronic) aquatic hazard, H411: Toxic to aquatic life with long lasting Category 2 effects.

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