N-(Isobutoxymethyl)acrylamide

Sigma-Aldrich Chemical Pvt Limited

Revision date : 2026-05-30

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GHS08 GHS05 GHS07
Health risk rating 5
Safety risk rating 1
Environmental risk rating 5

Note: Ingredients listed on restricted chemical lists

EC/CAS

240-715-7/79-06-1

Name of the chemical

Acrylamide

Concentration

>=3-<10

EC/CAS

201-173-7/924-42-5

Name of the chemical

N-(Hydroxymethyl)acrylamid; Methylolacrylamid; [NMA] (2020/1182)

Concentration

>=3-<10

EC/CAS

203-750-9/50-00-0

Name of the chemical

Formaldehyde

Concentration

>=0,1-<1

EC/CAS

213-103-2

Name of the chemical

N-(Hydroxymethyl)acrylamid; Methylolacrylamid; [NMA] (2020/1182)

Concentration

>=3-<10

EC/CAS

200-001-8

Name of the chemical

Formaldehyd (605/2014)

Concentration

>=25% 5-<25% 5-<25% >=5%

General Information

Version

8.2

Revision date

2026-05-30

Product name

N-(Isobutoxymethyl)acrylamide

CAS No.

16669-59-3

Icons in SDS

GHS05 GHS07 GHS08 M004 M017

Company Information

company name

Sigma-Aldrich Chemical Pvt Limited

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H302, H302+H312, H312, H315, H317, H318, H340, H350, H361, H373

Hazard statements

Code

Statements

H302

Harmful if swallowed

Section 2

SECTION 2: Hazards identification

Regulation (EC) No. 1272/2008 Classification of the substance or mixture

Signal word

Danger Danger

Hazard statements

H302 + H312 Harmful if swallowed or in contact with skin. H315 Causes skin irritation. H317 May cause an allergic skin reaction. H318 Causes serious eye damage. H340 May cause genetic defects. H350 May cause cancer. H361 Suspected of damaging fertility or the unborn child. H373 May cause damage to organs through prolonged or repeated exposure. H373 May cause damage to organs (Peripheral nervous system) through prolonged or repeated exposure if swallowed. EUH441 Strongly accumulates in the environment and living organisms including in humans. P202 Do not handle until all safety precautions have been read and understood. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. H317 May cause an allergic skin reaction. H340 May cause genetic defects. H350 May cause cancer. H361 Suspected of damaging fertility or the unborn child. H318 Causes serious eye damage. EUH441 Strongly accumulates in the environment and living organisms including in humans.

Prevention

Precautionary P201 Obtain special instructions before use.

Response

P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P391 Collect spillage.

Disposal

P501 Dispose of contents/ container to an approved waste disposal plant.

Additional information

Restricted to professional users. Reduced Labelling (<= 125 ml)

Precautionary statements

P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P391 Collect spillage. P501 Dispose of contents/ container to an approved waste disposal plant.

Supplemental label elements

none

2.3 Other hazards

This substance/mixture contains components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB).

ECOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

TOXICOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

2.1 Classification of the substance or mixture

Classification (REGULATION (EC) No 1272/2008) Acute toxicity, Category 4 H302: Harmful if swallowed. Acute toxicity, Category 4 H312: Harmful in contact with skin. Skin irritation, Category 2 H315: Causes skin irritation. Serious eye damage, Category 1 H318: Causes serious eye damage. Skin sensitisation, Category 1 H317: May cause an allergic skin reaction. Germ cell mutagenicity, Category H340: May cause genetic defects. 1B Carcinogenicity, Category 1B H350: May cause cancer. Reproductive toxicity, Category 2 H361: Suspected of damaging fertility or the unborn child. Specific target organ toxicity - H373: May cause damage to organs through repeated exposure, Category 2 prolonged or repeated exposure. Specific target organ toxicity - H373: May cause damage to organs through repeated exposure, Category 2, prolonged or repeated exposure if Peripheral nervous system swallowed. Persistent, bioaccumulative and EUH440: Accumulates in the environment toxic and living organisms including in humans. Very persistent and very EUH441: Strongly accumulates in the bioaccumulative environment and living organisms including in humans.

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