Note: Ingredients listed on restricted chemical lists
EC/CAS
200-659-6/67-56-1
Name of the chemical
Methanol
Concentration
>=90-< 100% 603-001-
EC/CAS
200-413-8
Name of the chemical
Methotrexate (INN)
Concentration
>=0.1-<1
General Information
Version
7.1
Revision date
2024-09-06
Product name
Methotrexate solution
1.2.1 Relevant identified uses
Laboratory chemicals, Synthesis of substances
1.2.2. Uses advised against
The product is being supplied under the TSCA R&D Exemption
Emergency telephone
800-424-9300, +1-703- 527-3887
Icons in SDS
Company Information
company name
Sigma-Aldrich Inc
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H225, H290, H301+H311+H331, H360, H370
Hazard statements
Code
Statements
H225
Highly Flammable liquid and vapour
Section 2
SECTION 2: Hazards identification
Classification of the substance or mixture
Signal word
Danger
Hazard statements
H225 Highly flammable liquid and vapor. H290 May be corrosive to metals. H301 + H311 + H331 Toxic if swallowed, in contact with skin or if inhaled. H360 May damage fertility or the unborn child. H370 Causes damage to organs (Eyes, Central nervous system).
Precautionary statements
P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P210 Keep away from heat/ sparks/ open flames/ hot surfaces. No smoking. P233 Keep container tightly closed. P234 Keep only in original container. P240 Ground/bond container and receiving equipment. P241 Use explosion-proof electrical/ ventilating/ lighting/ equipment. P242 Use only non-sparking tools. P243 Take precautionary measures against static discharge. P260 Do not breathe mist or vapors. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P301 + P310 + P330 IF SWALLOWED: Immediately call a POISON CENTER/ doctor. Rinse mouth. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower. P304 + P340 + P311 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/ doctor. P307 + P311 IF exposed: Call a POISON CENTER or doctor/ physician. P362 Take off contaminated clothing and wash before reuse. P370 + P378 In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish. P390 Absorb spillage to prevent material damage. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P403 + P235 Store in a well-ventilated place. Keep cool. P405 Store locked up. P406 Store in corrosive resistant container with a resistant inner liner. P501 Dispose of contents/ container to an approved waste disposal plant.
2.3 Other hazards
- none
2.1 Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) Flammable liquids (Category 2), H225 Corrosive to Metals (Category 1), H290 Acute toxicity, Oral (Category 3), H301 Acute toxicity, Inhalation (Category 3), H331 Acute toxicity, Dermal (Category 3), H311 Reproductive toxicity (Category 1B), H360 Specific target organ toxicity - single exposure (Category 1), Eyes, Central nervous system, H370 For the full text of the H-Statements mentioned in this Section, see Section 16.