General Information
Version
8.3
Revision date
2024-02-26
Product name
Ispinesib
CAS No.
336113-53-2
Emergency telephone
+44 (0)870 8200418
Icons in SDS
Company Information
company name
Merck Life Science UK Limited
e-mail address of the competent person responsible for the Safety Data Sheet
TechnicalService@merckgroup.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H300, H300+H330, H330, H341
Hazard statements
Code
Statements
H300
Fatal if swallowed
Section 2
SECTION 2: Hazards identification
Labelling according Regulation (EC) No 1272/2008 as amended by GB-CLP Classification of the substance or mixture
Signal word
Danger
Hazard statements
H300 + H330 Fatal if swallowed or if inhaled. H341 Suspected of causing genetic defects.
Precautionary statements
P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust. P264 Wash skin thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor.
Supplemental label elements
none
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
ECOLOGICAL INFORMATION
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
TOXICOLOGICAL INFORMATION
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. Caution: Physiologically highly active, therapeutically usable substance. The substance must be handled with the care required for hazardous materials.
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 as amended by GB-CLP Regulation, UK SI 2019/720, and UK SI 2020/1567 Acute toxicity, (Category 2) H300: Fatal if swallowed. Acute toxicity, (Category 2) H330: Fatal if inhaled. Germ cell mutagenicity, H341: Suspected of causing genetic (Category 2) defects.
