Note: Ingredients listed on restricted chemical lists
EC/CAS
225-863-2/5124-30-1
Name of the chemical
4,4'-methylenedicyclohexyl diisocyanate
Concentration
<= 100 %
General Information
Version
7.0
Revision date
2025-12-25
Product name
HMDI
CAS No.
5124-30-1
Emergency telephone
+44 (0)870 8200418
Icons in SDS
Company Information
company name
Merck Life Science UK Limited
e-mail address of the competent person responsible for the Safety Data Sheet
TechnicalService@merckgroup.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H315, H317, H319, H330, H334, H335
Hazard statements
Code
Statements
H315
Causes skin irritation
Section 2
SECTION 2: Hazards identification
Labelling according Regulation (EC) No 1272/2008 as amended by GB-CLP Classification of the substance or mixture
Signal word
Danger Danger
Hazard statements
H315 Causes skin irritation. H317 May cause an allergic skin reaction. H319 Causes serious eye irritation. H330 Fatal if inhaled. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H335 May cause respiratory irritation. H330 Fatal if inhaled. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H317 May cause an allergic skin reaction.
Precautionary statements
P260 Do not breathe mist or vapours. P264 Wash skin thoroughly after handling. P280 Wear protective gloves/ eye protection/ face protection. P302 + P352 IF ON SKIN: Wash with plenty of water. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P260 Do not breathe mist or vapours. P302 + P352 IF ON SKIN: Wash with plenty of water. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor.
Supplemental label elements
none "As from 24 August 2023 adequate training is required before industrial or professional use." Reduced Labelling (<= 125 ml) none
Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher
ECOLOGICAL INFORMATION
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
TOXICOLOGICAL INFORMATION
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. Lachrymator.
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 as amended by GB-CLP Regulation, UK SI 2019/720, and UK SI 2020/1567 Acute toxicity, (Category 2) H330: Fatal if inhaled. Skin irritation, (Category 2) H315: Causes skin irritation. Eye irritation, (Category 2) H319: Causes serious eye irritation. Respiratory sensitisation, H334: May cause allergy or asthma (Category 1) symptoms or breathing difficulties if inhaled. Skin sensitisation, (Category 1) H317: May cause an allergic skin reaction. Specific target organ toxicity - H335: May cause respiratory irritation. single exposure, (Category 3),