Hexamethylphosphoramide

Merck Life Science AB

Revision date : 2026-08-10

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GHS08 GHS05
Health risk rating 5
Safety risk rating 1
Environmental risk rating 1

Note: Ingredients listed on restricted chemical lists

EC/CAS

211-653-8/680-31-9

Name of the chemical

Hexamethylphosphoric triamide

Concentration

>=90-<=100

General Information

Version

7.6

Revision date

2026-08-10

Product name

Hexamethylphosphoramide

CAS No.

680-31-9

Emergency telephone

+(46)-852503403

Icons in SDS

GHS05 GHS08 M004 M009 M017

Company Information

company name

Merck Life Science AB

e-mail address of the competent person responsible for the Safety Data Sheet

TechnicalService@merckgroup.com

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H314, H318, H340, H350

Hazard statements

Code

Statements

H314

Causes severe skin burns and eye damage

Section 2

SECTION 2: Hazards identification

Regulation (EC) No. 1272/2008 Classification of the substance or mixture

Signal word

Danger

Hazard statements

H314 Causes severe skin burns and eye damage. H340 May cause genetic defects. H350 May cause cancer.

Precautionary statements

P202 Do not handle until all safety precautions have been read and understood. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.

Response

P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P363 Wash contaminated clothing before reuse.

Additional information

Restricted to professional users.

2.3 Other hazards

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

ECOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

TOXICOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

2.1 Classification of the substance or mixture

Classification (REGULATION (EC) No 1272/2008) Skin corrosion, Sub-category 1C H314: Causes severe skin burns and eye damage. Serious eye damage, Category 1 H318: Causes serious eye damage. Germ cell mutagenicity, Category H340: May cause genetic defects. 1B Carcinogenicity, Category 1B H350: May cause cancer.

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