EPA 8270 Semivolatile Internal Standard Mix

Merck Life Science UK Limited

Revision date : 2025-12-29

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GHS09 GHS07 GHS08
Health risk rating 5
Safety risk rating 1
Environmental risk rating 4

Note: Ingredients listed on restricted chemical lists

EC/CAS

200-838-9/75-09-2

Name of the chemical

Methylene chloride

Concentration

>=90-< 100%

General Information

Version

9.1

Revision date

2025-12-29

Product name

EPA 8270 Semivolatile Internal Standard Mix

REACH No

This

1.2.2. Uses advised against

For R&D use only. Not for pharmaceutical, household or other uses

Emergency telephone

+44 (0)870 8200418

Icons in SDS

GHS07 GHS08 GHS09

Company Information

company name

Merck Life Science UK Limited

e-mail address of the competent person responsible for the Safety Data Sheet

TechnicalService@merckgroup.com

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H315, H319, H336, H350, H411

Hazard statements

Code

Statements

H315

Causes skin irritation

Section 2

SECTION 2: Hazards identification

Labelling according Regulation (EC) No 1272/2008 as amended by GB-CLP Classification of the substance or mixture

Signal word

Danger Danger

Hazard statements

H315 Causes skin irritation. H319 Causes serious eye irritation. H336 May cause drowsiness or dizziness. H350 May cause cancer. H411 Toxic to aquatic life with long lasting effects. EUH441 Strongly accumulates in the environment and living organisms including in humans. H350 May cause cancer. EUH441 Strongly accumulates in the environment and living organisms including in humans.

Precautionary statements

P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P273 Avoid release to the environment. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P391 Collect spillage. P501 Dispose of contents/ container to an approved waste disposal plant. P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P273 Avoid release to the environment. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P391 Collect spillage. P501 Dispose of contents/ container to an approved waste disposal plant.

Supplemental label elements

none Restricted to professional users. Reduced Labelling (<= 125 ml) none

Other hazards

This substance/mixture contains components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB)

ECOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

TOXICOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

2.1 Classification of the substance or mixture

Classification according to Regulation (EC) No 1272/2008 as amended by GB-CLP Regulation, UK SI 2019/720, and UK SI 2020/1567 Skin irritation, (Category 2) H315: Causes skin irritation. Eye irritation, (Category 2) H319: Causes serious eye irritation. Carcinogenicity, (Category 1B) H350: May cause cancer. Specific target organ toxicity - H336: May cause drowsiness or dizziness. single exposure, (Category 3), Central nervous system Long-term (chronic) aquatic H411: Toxic to aquatic life with long lasting hazard, (Category 2) effects. Persistent, bioaccumulative and EUH440: Accumulates in the environment toxic and living organisms including in humans. Very persistent and very EUH441: Strongly accumulates in the bioaccumulative environment and living organisms including in humans.

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