Dapsone

Sigma-Aldrich Chemie GmbH

Revision date : 2025-11-03

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GHS09 GHS07 GHS08
Health risk rating 5
Safety risk rating 1
Environmental risk rating 4

Note: Ingredients listed on restricted chemical lists

EC/CAS

201-248-4/80-08-0

Name of the chemical

4,4′-diaminodiphenyl sulphone

Concentration

<= 100 %

General Information

Version

8.1

Revision date

2025-11-03

Product name

Dapsone

CAS No.

80-08-0

REACH No

A

Emergency telephone

+49 (0)696 43508409

Icons in SDS

GHS07 GHS08 GHS09 M004 M009 M017

Company Information

company name

Sigma-Aldrich Chemie GmbH

e-mail address of the competent person responsible for the Safety Data Sheet

technischerservice@merckgroup.com

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H302, H360F, H371, H373, H411

Hazard statements

Code

Statements

H302

Harmful if swallowed

Section 2

SECTION 2: Hazards identification

Regulation (EC) No. 1272/2008 Classification of the substance or mixture Acute toxicity, (Category 4) H302: Harmful if swallowed Reproductive toxicity, (Category H360F: May damage fertility 1B) Specific target organ toxicity - H371: May cause damage to organs single exposure, (Category 2), Blood Specific target organ toxicity - H373: May cause damage to organs repeated exposure, (Category 2), through prolonged or repeated exposure Blood, spleen, Liver Long-term (chronic) aquatic H411: Toxic to aquatic life with long lasting hazard, (Category 2) effects

Signal word

Danger Danger

Hazard statements

H302 Harmful if swallowed. H360F May damage fertility. H371 May cause damage to organs (Blood). H373 May cause damage to organs (Blood, spleen, Liver) through prolonged or repeated exposure. H411 Toxic to aquatic life with long lasting effects. Reduced Labelling (<= 125 ml) H360F May damage fertility.

Precautionary statements

P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust. P264 Wash skin thoroughly after handling. P273 Avoid release to the environment. P301 + P312 IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. P308 + P311 IF exposed or concerned: Call a POISON CENTER/ doctor. P202 Do not handle until all safety precautions have been read and understood.

Supplemental label elements

none none

2.3 Other hazards

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

ECOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

TOXICOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

2.1 Classification of the substance or mixture

Acute toxicity, (Category 4) H302: Harmful if swallowed. Reproductive toxicity, (Category H360F: May damage fertility. 1B) Specific target organ toxicity - H371: May cause damage to organs. single exposure, (Category 2), Blood Specific target organ toxicity - H373: May cause damage to organs repeated exposure, (Category 2), through prolonged or repeated exposure. Blood, spleen, Liver Long-term (chronic) aquatic H411: Toxic to aquatic life with long lasting hazard, (Category 2) effects.

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Safety – One-click access to first aid information.
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Labels – Generate Secondary Container Labels with just one click.