Cisplatin

Merck Life Science UK Limited

Revision date : 2025-06-25

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GHS08
Health risk rating 5
Safety risk rating 1
Environmental risk rating 1

General Information

Version

7.6

Revision date

2025-06-25

Product name

Cisplatin

CAS No.

15663-27-1

REACH No

A

Emergency telephone

+44 (0)870 8200418

Icons in SDS

GHS08 M004 M009 M017

Company Information

company name

Merck Life Science UK Limited

e-mail address of the competent person responsible for the Safety Data Sheet

TechnicalService@merckgroup.com

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H300, H315, H317, H319, H334, H335, H340, H350, H360FD

Hazard statements

Code

Statements

H300

Fatal if swallowed

Section 2

SECTION 2: Hazards identification

Regulation (EC) No. 1272/2008 Classification of the substance or mixture Acute toxicity, (Category 2) H300: Fatal if swallowed Skin irritation, (Category 2) H315: Causes skin irritation Eye irritation, (Category 2) H319: Causes serious eye irritation Respiratory sensitisation, H334: May cause allergy or asthma Category 1) symptoms or breathing difficulties if inhaled Skin sensitisation, (Category 1) H317: May cause an allergic skin reaction Germ cell mutagenicity, H340: May cause genetic defects Category 1B) Carcinogenicity, (Category 1B) H350: May cause cancer Reproductive toxicity, (Category H360FD: May damage fertility. May 1B) damage the unborn child Specific target organ toxicity - H335: May cause respiratory irritation single exposure, (Category 3), Respiratory system Label elements

Signal word

Danger Danger

Hazard statements

H300 Fatal if swallowed. H315 Causes skin irritation. H317 May cause an allergic skin reaction. H319 Causes serious eye irritation. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H335 May cause respiratory irritation. H340 May cause genetic defects. H350 May cause cancer. H360FD May damage fertility. May damage the unborn child. Reduced Labelling (<= 125 ml) H300 Fatal if swallowed. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H317 May cause an allergic skin reaction. H350 May cause cancer. H340 May cause genetic defects. H360FD May damage fertility. May damage the unborn child.

Precautionary statements

P202 Do not handle until all safety precautions have been read and understood. P261 Avoid breathing dust. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor. P302 + P352 IF ON SKIN: Wash with plenty of water. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P202 Do not handle until all safety precautions have been read and understood. P261 Avoid breathing dust. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor. P302 + P352 IF ON SKIN: Wash with plenty of water.

Supplemental label elements

none none

2.3 Other hazards

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

ECOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

TOXICOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

2.1 Classification of the substance or mixture

Acute toxicity, (Category 2) H300: Fatal if swallowed. Skin irritation, (Category 2) H315: Causes skin irritation. Eye irritation, (Category 2) H319: Causes serious eye irritation. Respiratory sensitisation, H334: May cause allergy or asthma (Category 1) symptoms or breathing difficulties if inhaled. Skin sensitisation, (Category 1) H317: May cause an allergic skin reaction. Germ cell mutagenicity, H340: May cause genetic defects. (Category 1B) Carcinogenicity, (Category 1B) H350: May cause cancer. Reproductive toxicity, (Category H360FD: May damage fertility. May 1B) damage the unborn child. Specific target organ toxicity - H335: May cause respiratory irritation. single exposure, (Category 3),

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