General Information
Version
6.11
Revision date
2026-07-02
Product name
β-Estradiol
CAS No.
50-28-2
Emergency telephone
+49 (0)696 43508409
Icons in SDS
Company Information
company name
Sigma-Aldrich Chemie GmbH
e-mail address of the competent person responsible for the Safety Data Sheet
technischerservice@merckgroup.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H351, H360Fd, H362, H410
Hazard statements
Code
Statements
H351
Suspected of causing cancer
Section 2
SECTION 2: Hazards identification
Regulation (EC) No. 1272/2008 Classification of the substance or mixture
Signal word
Danger Danger
Hazard statements
H351 Suspected of causing cancer. H360Fd May damage fertility. Suspected of damaging the unborn child. H362 May cause harm to breast-fed children. H410 Very toxic to aquatic life with long lasting effects. EUH380 May cause endocrine disruption in humans. EUH430 May cause endocrine disruption in the environment. H351 Suspected of causing cancer. H362 May cause harm to breast-fed children. EUH380 May cause endocrine disruption in humans. EUH430 May cause endocrine disruption in the environment. H360Fd May damage fertility. Suspected of damaging the unborn child.
Precautionary statements
P260 Do not breathe dust. P263 Avoid contact during pregnancy and while nursing. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P263 Avoid contact during pregnancy and while nursing. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P391 Collect spillage. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant.
Response
P308 + P313 IF exposed or concerned: Get medical advice/ attention. P391 Collect spillage.
Storage
P405 Store locked up.
Disposal
P501 Dispose of contents/ container to an approved waste disposal plant. Reduced Labelling (<= 125 ml)
Supplemental label elements
none
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
ECOLOGICAL INFORMATION
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
TOXICOLOGICAL INFORMATION
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
2.1 Classification of the substance or mixture
Classification (REGULATION (EC) No 1272/2008) Carcinogenicity, Category 2 H351: Suspected of causing cancer. Reproductive toxicity, Category 1A H360Fd: May damage fertility. Suspected of damaging the unborn child. Effects on or via lactation H362: May cause harm to breast-fed children. Endocrine disruptor for human EUH380: May cause endocrine disruption in health, Category 1 humans. Long-term (chronic) aquatic hazard, H410: Very toxic to aquatic life with long Category 1 lasting effects. Endocrine disruptor for EUH430: May cause endocrine disruption in environment, Category 1 the environment.