β-Estradiol

Sigma-Aldrich Chemie GmbH

Revision date : 2026-07-02

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GHS08 GHS09
Health risk rating 5
Safety risk rating 1
Environmental risk rating 5

General Information

Version

6.11

Revision date

2026-07-02

Product name

β-Estradiol

CAS No.

50-28-2

Emergency telephone

+49 (0)696 43508409

Icons in SDS

GHS08 GHS09 M004 M009 M017

Company Information

company name

Sigma-Aldrich Chemie GmbH

e-mail address of the competent person responsible for the Safety Data Sheet

technischerservice@merckgroup.com

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H351, H360Fd, H362, H410

Hazard statements

Code

Statements

H351

Suspected of causing cancer

Section 2

SECTION 2: Hazards identification

Regulation (EC) No. 1272/2008 Classification of the substance or mixture

Signal word

Danger Danger

Hazard statements

H351 Suspected of causing cancer. H360Fd May damage fertility. Suspected of damaging the unborn child. H362 May cause harm to breast-fed children. H410 Very toxic to aquatic life with long lasting effects. EUH380 May cause endocrine disruption in humans. EUH430 May cause endocrine disruption in the environment. H351 Suspected of causing cancer. H362 May cause harm to breast-fed children. EUH380 May cause endocrine disruption in humans. EUH430 May cause endocrine disruption in the environment. H360Fd May damage fertility. Suspected of damaging the unborn child.

Precautionary statements

P260 Do not breathe dust. P263 Avoid contact during pregnancy and while nursing. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P263 Avoid contact during pregnancy and while nursing. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P391 Collect spillage. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant.

Response

P308 + P313 IF exposed or concerned: Get medical advice/ attention. P391 Collect spillage.

Storage

P405 Store locked up.

Disposal

P501 Dispose of contents/ container to an approved waste disposal plant. Reduced Labelling (<= 125 ml)

Supplemental label elements

none

2.3 Other hazards

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

ECOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

TOXICOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

2.1 Classification of the substance or mixture

Classification (REGULATION (EC) No 1272/2008) Carcinogenicity, Category 2 H351: Suspected of causing cancer. Reproductive toxicity, Category 1A H360Fd: May damage fertility. Suspected of damaging the unborn child. Effects on or via lactation H362: May cause harm to breast-fed children. Endocrine disruptor for human EUH380: May cause endocrine disruption in health, Category 1 humans. Long-term (chronic) aquatic hazard, H410: Very toxic to aquatic life with long Category 1 lasting effects. Endocrine disruptor for EUH430: May cause endocrine disruption in environment, Category 1 the environment.

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