Aminopterin

Merck Life Science UK Limited

Revision date : 2024-01-09

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GHS08 GHS06
Health risk rating 5
Safety risk rating 1
Environmental risk rating 1

General Information

Version

8.2

Revision date

2024-01-09

Product name

Aminopterin

CAS No.

54-62-6

REACH No

A

Emergency telephone

+44 (0)870 8200418

Icons in SDS

GHS06 GHS08 M004 M009 M017

Company Information

company name

Merck Life Science UK Limited

e-mail address of the competent person responsible for the Safety Data Sheet

TechnicalService@merckgroup.com

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H300, H315, H319, H341, H360FD

Hazard statements

Code

Statements

H300

Fatal if swallowed

Section 2

SECTION 2: Hazards identification

Labelling according Regulation (EC) No 1272/2008 as amended by GB-CLP Classification of the substance or mixture

Signal word

Danger Danger

Hazard statements

H300 Fatal if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation. H341 Suspected of causing genetic defects. H360FD May damage fertility. May damage the unborn child. H300 Fatal if swallowed. H341 Suspected of causing genetic defects. H360FD May damage fertility. May damage the unborn child.

Precautionary statements

P202 Do not handle until all safety precautions have been read and understood. P264 Wash skin thoroughly after handling. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor. P302 + P352 IF ON SKIN: Wash with plenty of water. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P202 Do not handle until all safety precautions have been read and understood. P264 Wash skin thoroughly after handling. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor.

Supplemental label elements

none Reduced Labeling (<= 125 ml) none

Other hazards

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher

ECOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

TOXICOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

2.1 Classification of the substance or mixture

Classification according to Regulation (EC) No 1272/2008 as amended by GB-CLP Regulation, UK SI 2019/720, and UK SI 2020/1567 Acute toxicity, (Category 1) H300: Fatal if swallowed. Skin irritation, (Category 2) H315: Causes skin irritation. Eye irritation, (Category 2) H319: Causes serious eye irritation. Germ cell mutagenicity, H341: Suspected of causing genetic (Category 2) defects. Reproductive toxicity, (Category H360FD: May damage fertility. May 1B) damage the unborn child.

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