4,4′-Diaminodiphenylmethane

Sigma-Aldrich Chemical Pvt Limited

Revision date : 2025-12-24

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GHS06 GHS08 GHS09
Health risk rating 5
Safety risk rating 1
Environmental risk rating 5

Note: Ingredients listed on restricted chemical lists

General Information

Version

7.10

Revision date

2025-12-24

Product name

4,4′-Diaminodiphenylmethane

CAS No.

101-77-9

Icons in SDS

GHS06 GHS08 GHS09 M004 M009 M017

Company Information

company name

Sigma-Aldrich Chemical Pvt Limited

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H301, H317, H341, H350, H370, H373, H400, H410, H411

Hazard statements

Code

Statements

H301

Toxic if swallowed

Section 2

SECTION 2: Hazards identification

Regulation (EC) No. 1272/2008 Classification of the substance or mixture

Signal word

Danger Danger

Hazard statements

H301 Toxic if swallowed. H317 May cause an allergic skin reaction. H341 Suspected of causing genetic defects. H350 May cause cancer. H370 Causes damage to organs (Liver, eye - retina). H373 May cause damage to organs (Liver) through prolonged or repeated exposure. H410 Very toxic to aquatic life with long lasting effects. H301 Toxic if swallowed. H317 May cause an allergic skin reaction. H341 Suspected of causing genetic defects. H350 May cause cancer. H370 Causes damage to organs.

Precautionary statements

P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor. P302 + P352 IF ON SKIN: Wash with plenty of water.

Response

P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor. P302 + P352 IF ON SKIN: Wash with plenty of water.

Additional information

Restricted to professional users. Reduced Labelling (<= 125 ml)

Supplemental label elements

none

2.3 Other hazards

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

ECOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

TOXICOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

2.1 Classification of the substance or mixture

Classification (REGULATION (EC) No 1272/2008) Acute toxicity, Category 3 H301: Toxic if swallowed. Skin sensitisation, Category 1 H317: May cause an allergic skin reaction. Germ cell mutagenicity, Category 2 H341: Suspected of causing genetic defects. Carcinogenicity, Category 1B H350: May cause cancer. Specific target organ toxicity - H370: Causes damage to organs. single exposure, Category 1, Liver, eye - retina Specific target organ toxicity - H373: May cause damage to organs through repeated exposure, Category 2, prolonged or repeated exposure. Liver Short-term (acute) aquatic hazard, H400: Very toxic to aquatic life. Category 1 Long-term (chronic) aquatic hazard, H411: Toxic to aquatic life with long lasting Category 2 effects.

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