Note: Ingredients listed on restricted chemical lists
EC/CAS
67-56-1
Name of the chemical
Methanol
Concentration
>=80-<=100
EC/CAS
123-91-1
Name of the chemical
1,4-Dioxane
Concentration
>=0.1-<=1
General Information
Version
6.14
Revision date
2026-07-22
Product name
1,4-Dioxane solution
1.2.1 Relevant identified uses
Laboratory chemicals, Synthesis of substances
Emergency telephone
800-424-9300, +1-703- 527-3887
Icons in SDS
Company Information
company name
Sigma-Aldrich Inc
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H225, H301+H311+H331, H350, H370
Hazard statements
Code
Statements
H225
Highly Flammable liquid and vapour
Section 2
SECTION 2: Hazards identification
Other hazards
None known
Signal word
Danger
Hazard statements
H225 Highly flammable liquid and vapour. H301 + H311 + H331 Toxic if swallowed, in contact with skin or if inhaled. H350 May cause cancer. H370 Causes damage to organs (Eyes, Central nervous system).
Prevention
P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P233 Keep container tightly closed. P240 Ground and bond container and receiving equipment. P241 Use explosion-proof electrical/ ventilating/ lighting P242 Use non-sparking tools. P243 Take action to prevent static discharges. P260 Do not breathe mist or vapours. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves, protective clothing, eye protection and face protection.
Response
P301 + P310 + P330 IF SWALLOWED: Immediately call a POISON CENTER/ doctor. Rinse mouth. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower. P304 + P340 + P311 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/ doctor. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P361 + P364 Take off immediately all contaminated clothing and wash it before reuse. P370 + P378 In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish.
Storage
P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P403 + P235 Store in a well-ventilated place. Keep cool. P405 Store locked up.
Disposal
P501 Dispose of contents/ container to an approved waste disposal plant.
2.1 Classification of the substance or mixture
(29 CFR 1910.1200) Hazards for the product as supplied Flammable liquids : Category 2 Acute toxicity (Oral) : Category 3 Acute toxicity : Category 3 (Inhalation) Acute toxicity (Dermal) : Category 3 Carcinogenicity : Category 1B Specific target organ : Category 1 (Eyes, Central nervous system) toxicity - single exposure Other hazards