1,4-Dioxane solution

Sigma-Aldrich Inc

Revision date : 2026-06-02

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GHS06 GHS08 GHS07
Health risk rating 4
Safety risk rating 1
Environmental risk rating 1

General Information

Version

8.7

Revision date

2026-06-02

Product name

1,4-Dioxane solution

1.2.1 Relevant identified uses

Laboratory chemicals, Synthesis of substances

Emergency telephone

800-424-9300, +1-703- 527-3887

Icons in SDS

GHS06 GHS07 GHS08 M004 M010 M011 M017

Company Information

company name

Sigma-Aldrich Inc

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H302, H315, H319, H331, H336, H351, H361, H372, H402

Hazard statements

Code

Statements

H302

Harmful if swallowed

Section 2

SECTION 2: Hazards identification

Other hazards

None known

Signal word

Danger

Hazard statements

H302 Harmful if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation. H331 Toxic if inhaled. H336 May cause drowsiness or dizziness. H351 Suspected of causing cancer. H361 Suspected of damaging fertility or the unborn child. H372 Causes damage to organs (Liver, Kidney) through prolonged or repeated exposure. H402 Harmful to aquatic life.

Prevention

P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe mist or vapours. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.

Response

P301 + P312 + P330 IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. Rinse mouth. P302 + P352 IF ON SKIN: Wash with plenty of water. P304 + P340 + P311 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/ doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P332 + P313 If skin irritation occurs: Get medical P337 + P313 If eye irritation persists: Get medical

Storage

P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.

Disposal

P501 Dispose of contents/ container to an approved waste disposal plant.

2.1 Classification of the substance or mixture

(29 CFR 1910.1200) Hazards for the product as supplied Acute toxicity (Oral) : Category 4 Acute toxicity : Category 3 (Inhalation) Skin irritation : Category 2 Eye irritation : Category 2A Carcinogenicity : Category 2 Reproductive toxicity : Category 2 Specific target organ : Category 3 (Central nervous system) toxicity - single exposure Specific target organ : Category 1 (Liver, Kidney) toxicity - repeated exposure Short-term (acute) : Category 3 aquatic hazard Other hazards

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