1,4-Dioxane solution

Merck Life Science N.V

Revision date : 2024-01-12

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GHS07 GHS08 GHS02
Health risk rating 5
Safety risk rating 5
Environmental risk rating 3

Note: Ingredients listed on restricted chemical lists

General Information

Version

6.14

Revision date

2024-01-12

Product name

1,4-Dioxane solution

1.2.2. Uses advised against

For R&D use only. Not for pharmaceutical, household or other uses

Emergency telephone

+(31)-858880596

Icons in SDS

GHS02 GHS07 GHS08 M004 M010 M011 M017

Company Information

company name

Merck Life Science N.V

e-mail address of the competent person responsible for the Safety Data Sheet

technischeservicebenelux@merckgroup.com

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H225, H304, H315, H319, H335, H340, H350, H372, H412

Hazard statements

Code

Statements

H225

Highly Flammable liquid and vapour

Section 2

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture

Flammable liquids, (Category 2) H225: Highly flammable liquid and vapor. Skin irritation, (Category 2) H315: Causes skin irritation. Eye irritation, (Category 2) H319: Causes serious eye irritation. Germ cell mutagenicity, H340: May cause genetic defects. (Category 1B) Carcinogenicity, (Category 1A) H350: May cause cancer. Specific target organ toxicity - H335: May cause respiratory irritation. single exposure, (Category 3), Respiratory system Specific target organ toxicity - H372: Causes damage to organs through repeated exposure, (Category 1), prolonged or repeated exposure. Blood Aspiration hazard, (Category 1) H304: May be fatal if swallowed and enters airways. Long-term (chronic) aquatic H412: Harmful to aquatic life with long hazard, (Category 3) lasting effects.

Aspiration hazard

(Category 1) H304 May be fatal if swallowed and enters airways. Long-term (chronic) aquatic H412: Harmful to aquatic life with long hazard, (Category 3) lasting effects.

Signal word

Danger Danger

Hazard statements

H225 Highly flammable liquid and vapor. H304 May be fatal if swallowed and enters airways. H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. H340 May cause genetic defects. H350 May cause cancer. H372 Causes damage to organs (Blood) through prolonged or repeated exposure. H412 Harmful to aquatic life with long lasting effects. H340 May cause genetic defects. H350 May cause cancer. H372 Causes damage to organs through prolonged or repeated exposure. H304 May be fatal if swallowed and enters airways. H412 Harmful to aquatic life with long lasting effects.

Precautionary statements

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P273 Avoid release to the environment. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P331 Do NOT induce vomiting. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor. P331 Do NOT induce vomiting.

Supplemental label elements

EUH019 May form explosive peroxides. Restricted to professional users. Reduced Labeling (<= 125 ml) EUH019 May form explosive peroxides.

Other hazards

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher

ECOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

TOXICOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

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