Note: Ingredients listed on restricted chemical lists
EC/CAS
204-661-8/123-91-1
Name of the chemical
1,4-Dioxane
Concentration
>=90-<=100
General Information
Version
8.5
Revision date
2025-12-25
Product name
1,4-Dioxane
CAS No.
123-91-1
REACH No
01-2119462837-26-XXXX
Emergency telephone
+(47)-22591300, +(47)-21930678
Icons in SDS
Company Information
company name
Merck Life Science AS
e-mail address of the competent person responsible for the Safety Data Sheet
TechnicalService@merckgroup.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H225, H319, H335, H350
Hazard statements
Code
Statements
H225
Highly Flammable liquid and vapour
Section 2
SECTION 2: Hazards identification
Regulation (EC) No. 1272/2008 Classification of the substance or mixture
Signal word
Danger Danger
Hazard statements
H225 Highly flammable liquid and vapour. H319 Causes serious eye irritation. H335 May cause respiratory irritation. H350 May cause cancer. EUH066 Repeated exposure may cause skin dryness or cracking. H350 May cause cancer.
Supplemental label elements
EUH019 May form explosive peroxides. EUH019 May form explosive peroxides. EUH066 Repeated exposure may cause skin dryness or cracking.
Precautionary statements
P202 Do not handle until all safety precautions have been read and understood. P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P233 Keep container tightly closed. P240 Ground and bond container and receiving equipment. P202 Do not handle until all safety precautions have been read and understood. P308 + P313 IF exposed or concerned: Get medical advice/ attention.
Response
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention.
Additional information
Restricted to professional users. Reduced Labelling (<= 125 ml)
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
ECOLOGICAL INFORMATION
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
TOXICOLOGICAL INFORMATION
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
2.1 Classification of the substance or mixture
Classification (REGULATION (EC) No 1272/2008) Flammable liquids, Category 2 H225: Highly flammable liquid and vapour. Eye irritation, Category 2 H319: Causes serious eye irritation. Carcinogenicity, Category 1B H350: May cause cancer. Specific target organ toxicity - H335: May cause respiratory irritation. single exposure, Category 3,