Florfenicol (300 mg/mL)-Flunixin (16.5 mg/mL)-2-Pyrrolidone Injectable Solution

SECTION 2: Hazards identification

OSHA EMERGENCY OVERVIEW Solution Yellow-brown Odor unknown Toxic by inhalation. May be harmful if swallowed. Irritating to eyes. May cause allergic reactions in susceptible individuals. May cause effects to: gastrointestinal tract respiratory system blood liver kidney male reproductive system fetus May cause impaired fertility. May cause developmental effects. Toxic to aquatic organisms. May cause long-term adverse effects in the aquatic environment.

Potential health effects

The toxicological properties of the mixture(s) have not been fully characterized in humans or animals. However, there are data to describe the toxicological properties of the individual ingredients. The following summary is based upon available information about the individual ingredients of the mixture(s), or of the expected properties of the mixture(s). Florfenicol is a broad spectrum antibiotic used in veterinary products. Florfenicol may cause allergic reactions in susceptible individuals. Based on animal studies, florfenicol may cause slight eye irritation, constipation, changes in blood cell counts, changes in stool, or liver effects. It may also cause developmental effects or effects to male reproductive organs. Flunixin meglumine is a potent non-narcotic, non-steroidal agent with pain killing, anti-inflammatory, and fever-reducing activity. Based on animal studies, flunixin meglumine may cause severe eye irritation or irreversible ocular effects. It may also cause irritation of the skin, mucous membranes, respiratory tract, and gastrointestinal tract. Repeated dermal contact to high concentrations may cause severe skin irritation. Prolonged inhalation may produce serious lung effects. Repeated ingestion or inhalation of high doses may cause internal bleeding, predominantly of the gastrointestinal tract. Glyceryl triacetate may cause slight to moderate eye irritation based on animal studies. 2-Pyrrolidone may cause fetal effects based on animal studies. Malic acid is a relatively strong acid. It may cause severe eye irritation, and skin and mucous membrane irritation. LISTED CARCINOGENS