Temozolomide Formulation

Hazard statements (CLP)

H300, H319, H341, H351, H360FD, H372

Code

Statements

H300

Fatal if swallowed

OSHA HCS Classification

Combustible dust Acute toxicity (Oral) Category 2 Eye irritation Category 2A Germ cell mutagenicity Category 2 Carcinogenicity Category 2 Reproductive toxicity Category 1B Specific target organ Category 1 (Bone marrow, thymus gland, lymph node, spleen) systemic toxicity - repeated exposure (Oral)

Signal word

Danger

Hazard statements

If small particles are generated during further processing, handling or by other means, may form combustible dust concentrations in air. H300 Fatal if swallowed. H319 Causes serious eye irritation. H341 Suspected of causing genetic defects. H351 Suspected of causing cancer. H360FD May damage fertility. May damage the unborn child. H372 Causes damage to organs (Bone marrow, thymus gland, lymph node, spleen) through prolonged or repeated exposure if swallowed.

Prevention

P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.

Response

P301 + P310 + P330 IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ atten- tion.

Storage

P405 Store locked up.

Disposal

P501 Dispose of contents/ container to an approved waste dis- posal plant.

2.3 Other hazards

Contact with dust can cause mechanical irritation or drying of the skin.