GLYCERINE

SECTION 2: Hazards identification

Classification of the substance or mixture Classification (SI 2019 No. 720) Physical hazards Not Classified 19-20 Sandleheath Industrial Estate, Fordingbridge, Hampshire, SP6 1PA, UK

Health hazards

Not Classified

Environmental hazards

Not Classified

2.2 Label elements

EC number 200-289-5

Hazard statements

NC Not Classified

Contains

GLYCEROL

2.1 Classification of the substance or mixture

Classification (SI 2019 No. 720) Physical hazards Not Classified 19-20 Sandleheath Industrial Estate, Fordingbridge, Hampshire, SP6 1PA, UK Health hazards Not Classified Environmental hazards Not Classified 2.2. Label elements EC number 200-289-5 Hazard statements NC Not Classified Contains GLYCEROL 2.3. Other hazards SECTION 3: Composition/information on ingredients 3.2. Mixtures GLYCEROL 99.5% CAS number: 56-81-5 EC number: 200-289-5 Classification Not Classified The full text for all hazard statements is displayed in Section 16. SECTION 4: First aid measures 4.1. Description of first aid measures General information Ensure that medical personnel are aware of the materials involved and take precautions to protect themselves. In all cases of doubt, or when symptoms persist, seek medical attention. Inhalation Remove person to fresh air and keep comfortable for breathing. Get medical attention. Ingestion Rinse mouth. Do not induce vomiting unless under the direction of medical personnel. Get medical attention. Skin contact Wash skin thoroughly with soap and water. Eye contact Flush eyes thoroughly with water for several minutes. Remove contact lenses after the initial 1-2 minutes and continue flushing for several additional minutes. If effects occur, consult a physician, preferably an ophthalmologist. Protection of first aiders First aid personnel should wear appropriate protective equipment during any rescue. 4.2. Most important symptoms and effects, both acute and delayed General information No information available. Inhalation No information available. Ingestion Ingestion of large quantities may cause: Headache. Dizziness. Nausea, vomiting. Diarrhoea. Skin contact Causes mild skin irritation. Eye contact Irritation of eyes and mucous membranes. 4.3. Indication of any immediate medical attention and special treatment needed Specific treatments No information available. Notes for the doctor Treat symptomatically. SECTION 5: Firefighting measures 5.1. Extinguishing media 19-20 Sandleheath Industrial Estate, Fordingbridge, Hampshire, SP6 1PA, UK Suitable extinguishing media Water spray, fog or mist. Dry chemicals. Carbon dioxide (CO2). Foam. Unsuitable extinguishing Do not use water jet as an extinguisher, as this will spread the fire. media 5.2. Special hazards arising from the substance or mixture Specific hazards Violent steam generation or eruption may occur upon application of direct water stream to hot liquids. Hazardous combustion Carbon monoxide (CO). Carbon dioxide (CO2). Pyrolysis products. Toxic gases or vapours. products Irritating gases or vapours. 5.3. Advice for firefighters Protective actions during Keep people away. Isolate fire and deny unnecessary entry. Dilute burning liquid with large firefighting amounts of water. In case of fire and/or explosion do not breathe fumes. Extinguishing materials should be selected according to the surrounding area Prevent run-off from the fire fighting to enter drains or water courses. Fight fire with normal precautions from a reasonable distance. Special protective equipment Wear positive-pressure self-contained breathing apparatus (SCBA) and appropriate protective for firefighters clothing. EN133 If protective equipment is not available or not used, fight fire from a protected location or safe distance. SECTION 6: Accidental release measures 6.1. Personal precautions, protective equipment and emergency procedures Personal precautions Wear protective clothing as described in Section 8 of this safety data sheet. Ventilate spillage area Special danger of slipping by leaking/ spilling product. Wear suitable protective equipment, including gloves, goggles/face shield, respirator, boots, clothing or apron, as appropriate. Keep unnecessary and unprotected personnel away from the spillage. For non-emergency personnel No information available. For emergency responders Use self-contained breathing apparatus. 6.2. Environmental precautions Environmental precautions Do not allow product to reach soil, waterways, drains and sewers. Retain contaminated washing water and dispose 6.3. Methods and material for containment and cleaning up Methods for cleaning up Absorb spilled liquid with inert absorbent. Collect spillage. Place in suitable containers for disposal, labelled appropriately. Ventilate area and exercise caution 6.4. Reference to other sections Reference to other sections See Section 7 for information on safe handling. For personal protection, see Section 8. See Section 11 for additional information on health hazards. See Section 12 for additional information on ecological hazards. For waste disposal, see Section 13. SECTION 7: Handling and storage 7.1. Precautions for safe handling Usage precautions Container must be kept tightly closed when not in use. Advice on general Avoid contact with eyes and skin. Do not eat, drink or smoke when using this product. Eye occupational hygiene wash facilities and emergency shower must be available when handling this product. Good personal hygiene procedures should be implemented. Wash skin thoroughly after handling. Take off immediately all contaminated clothing and wash it before reuse. 7.2. Conditions for safe storage, 19-20 including Sandleheath any Industrial incompatibilities Estate, Fordingbridge, Hampshire, SP6 1PA, UK Storage precautions Store in tightly-closed, original container in a dry and cool place. Protect from moisture. Protect from humidity: Keep container tightly closed and dry. Keep away from heat. General ventilation required. Storage class No information available. 7.3. Specific end use(s) Specific end use(s) The identified uses for this product are detailed in Section 1.2. Usage description No information available. SECTION 8: Exposure controls/Personal protection 8.1. Control parameters Occupational exposure limits No information available. GLYCEROL Long-term exposure limit (8-hour TWA): WEL 10 mg/m³ WEL = Workplace Exposure Limit. Ingredient comments No information available. Biological limit values No information available. DNEL Workers - Inhalation; Long term local effects: 56 mg/m³ General population - Inhalation; Long term local effects: 33 mg/m³ General population - Oral; Long term systemic effects: 229 mg/kg/day DMEL No information available. PNEC Fresh water; 0.885 mg/l marine water; 0.088 mg/l STP; 1000 mg/l Sediment (Freshwater); 3.3 mg/kg Sediment (Marinewater); 0.33 mg/kg Soil; 0.141 mg/kg 8.2. Exposure controls Protective equipment Appropriate engineering As this product contains ingredients with exposure limits, process enclosures, local exhaust controls ventilation or other engineering controls should be used to keep worker exposure below any statutory or recommended limits, if use generates dust, fumes, gas, vapour or mist. Emergency shower and eye wash facilities should be readily available Use approved respirator if air contamination is above an acceptable level. Personal protection No information available. Eye/face protection Personal protective equipment that provides appropriate eye and face protection should be worn. Safety glasses with side shields conforming to EN166 19-20 Sandleheath Industrial Estate, Fordingbridge, Hampshire, SP6 1PA, UK Hand protection To protect hands from chemicals, wear gloves that are proven to be impervious to the chemical and resist degradation. Wash contaminated gloves before reuse. It is recommended that gloves are made of the following material: Butyl rubber. Polyethylene. Neoprene. Natural rubber Polyvinyl chloride (PVC). Nitrile rubber. Polyvinyl alcohol (PVA). When prolonged or frequently repeated contact may occur, a glove with a protection class of 4 or higher (breakthrough time greater than 120 minutes according to EN 374) is recommended. When only brief contact is expected, a glove with a protection class of 1 or higher (breakthrough time greater than 10 minutes according to EN 374) is recommended. Thickness > or = 0,2mm. Other skin and body Body protection must be chosen depending on activity and possible exposure, eg. apron, protection protecting boots, chemical-protection suit (according to DIN-EN 465). Chemical resistant boots should comply with European standard EN345. Hygiene measures Avoid contact with skin, eyes and clothing Do not eat, drink or smoke when using this product. Eye wash facilities and emergency shower must be available when handling this product. Good personal hygiene procedures should be implemented. Wash skin thoroughly after handling. Take off immediately all contaminated clothing and wash it before reuse. Keep away from foodstuffs, beverages and feed. Respiratory protection If ventilation is inadequate, suitable respiratory protection must be worn. type AP2 Thermal hazards Contact with hot product can cause serious thermal burns. Wear appropriate thermal protective clothing, when necessary. Environmental exposure Avoid discharge into the environment. controls SECTION 9: Physical and chemical properties 9.1. Information on basic physical and chemical properties Appearance Semi-viscous liquid. Colour Colourless. Odour Odourless. Odour threshold No information available. pH pH (concentrated solution): 5-9 20 °C Melting point 18.17°C klimisch rating 2 1953 1925 Initial boiling point and range 290°C @ 760 mm Hg klimisch rating 2 1953 1924 Flash point 177 - 199°C Closed cup. klimisch rating 2 1994 2002 Evaporation rate No information available. Evaporation factor No information available. Flammability (solid, gas) Not flammable. Upper/lower flammability or No information available. explosive limits Other flammability No information available. Vapour pressure 0.195 mm Hg @ 100°C klimisch rating 2 1953 Vapour density No information available. Relative density 1.261 @ 20°C klimisch rating 2 1953 Bulk density No information available. 19-20 Sandleheath Industrial Estate, Fordingbridge, Hampshire, SP6 1PA, UK Solubility(ies) 1000000 mg/l water @ 25°C klimisch rating 2 1997 1986 Partition coefficient log Pow: -1.75 klimisch rating 2 1980 1971 1995 OECD guideline 107 Auto-ignition temperature 370°C klimisch rating 2 2002 Decomposition Temperature No information available. Viscosity 1 412 mPa s @ 20°C klimisch rating 2 1953 OECD 114 1,300 - 1,412 mPa s @ 20°C Dynamic viscosity. Explosive properties No information available. Explosive under the influence No information available. of a flame Oxidising properties No information available. Comments No information available. 9.2. Other information Other information No information available. Refractive index No information available. Particle size No information available. Molecular weight No information available. Volatility No information available. Saturation concentration No information available. Critical temperature No information available. Volatile organic compound No information available. SECTION 10: Stability and reactivity 10.1. Reactivity Reactivity Stable under normal conditions 10.2. Chemical stability Stability The substance is hygroscopic and will absorb water by contact with the moisture in the air. 10.3. Possibility of hazardous reactions Possibility of hazardous In use may form flammable/explosive vapour-air mixture. reactions 10.4. Conditions to avoid Conditions to avoid Keep away from heat, sparks and open flame. Avoid heat, flames and other sources of ignition. Water, moisture. No smoking. 10.5. Incompatible materials Materials to avoid Avoid contact with strong oxidising agents. 10.6. Hazardous decomposition products Hazardous decomposition At high temperatures acrolein may be formed. In the event of a fire, see section 5 products SECTION 11: Toxicological information 11.1. Information on toxicological 19-20 effects Sandleheath Industrial Estate, Fordingbridge, Hampshire, SP6 1PA, UK Toxicological effects No information available. Other health effects No information available. Acute toxicity - oral Notes (oral LD₅₀) LD₅₀ 27 mg/kg, bw, Oral, Rat Klimisch rating 1 LD₅₀ ca. 23 000 mg/kg, bw, Oral, Mouse 1953 Klimisch rating 2 1953 LD₅₀ >= 10 000 mg/kg, bw, Oral, Guinea pig Klimisch rating 2 1953 Acute toxicity - dermal Notes (dermal LD₅₀) LD₅₀ 45 ml/kg, bw, Dermal, Guinea pig Klimisch rating 2 1938 Acute toxicity - inhalation Notes (inhalation LC₅₀) LC50 4 655 mg-min/liter, Inhalation, Rat klimisch rating 2 1967 Skin corrosion/irritation Not irritating. Animal data Dose: 0.5 ml, 24 hours, Rabbit Klimisch rating 2 1971 Not irritating. Human skin model test No information available. Extreme pH No information available. Serious eye damage/irritation Dose: 0.1 ml, 7 days, Rabbit klimisch rating 2 1971 Not irritating. Dose: 0.1 ml, 1 hour, Rabbit klimisch rating 2 1953 Not irritating. Respiratory sensitisation No information available. Skin sensitisation No information available. Germ cell mutagenicity Genotoxicity - in vitro Bacterial reverse mutation test: Negative. Klimisch rating 2 1983 Bacterial reverse mutation test: Negative. Klimisch rating 2 1988 OECD471 Mammalian cell micronucleus test: Negative. Klimisch rating 2 1988 OECD476 Sister chromatid exchange assay in mammalian cells: Negative. Klimisch rating 2 1988 OECD476 DNA damage and/or repair: Negative. Klimisch rating 2 1988 OECD 482 Chromosome aberration: Negative. Klimisch rating 2 1988 OECD473 Bacterial reverse mutation test: Negative. Klimisch rating 2 1983 Genotoxicity - in vivo No information available. Carcinogenicity No information available. Target organ for No information available. carcinogenicity IARC carcinogenicity No information available. NTP carcinogenicity No information available. Reproductive toxicity Reproductive toxicity - fertility No information available. Reproductive toxicity - Maternal toxicity: - NOAEL: 1310 mg/kg/day, Oral, Rat Developmental toxicity: - NOAEL: 1310 development mg/kg/day, Oral, Rat Klimisch rating 2 1974 Maternal toxicity: - NOAEL: 1280 mg/kg/day, Oral, Mouse Developmental toxicity: - NOAEL: 1280 mg/kg/day, Oral, Mouse Klimisch rating 2 1974 Maternal toxicity: - NOAEL: 1180 mg/kg/day, Oral, Rabbit Developmental toxicity: - NOAEL: 1180 mg/kg/day, Oral, Rabbit Klimisch rating 2 1974 19-20 Sandleheath Industrial Estate, Fordingbridge, Hampshire, SP6 1PA, UK Specific target organ toxicity - single exposure STOT - single exposure No information available. Target organs No information available. Specific target organ toxicity - repeated exposure STOT - repeated exposure NOAEL 8000-10,000 mg/kg, bw, Oral, Rat Klimisch rating 2 1953 OECD 452 NOEL 50 000 ppm, Oral, Rat LOEL 200 000 ppm, Oral, Rat Klimisch rating 2 1962 NOAEL 167 mg/m³, Inhalation, Rat Klimisch rating 2 1992 NOEL 4 ml/kg, Dermal, Rabbit Klimisch rating 2 1953 Target organs No information available. Aspiration hazard No information available. Toxicokinetics No information available. General information No information available. Inhalation Spray/mists may cause respiratory tract irritation. Ingestion May cause discomfort if swallowed. Skin contact Prolonged skin contact may cause temporary irritation. Eye contact May cause discomfort. Acute and chronic health No information available. hazards Route of exposure No information available. Target organs No information available. Medical symptoms