Note: Ingredients listed on restricted chemical lists
EC/CAS
123-91-1
Name of the chemical
1,4-Dioxane
Concentration
N/A
EC/CAS
7732-18-5
Name of the chemical
Water, distilled, conductivity or of similar purity H2O
Concentration
N/A
EC/CAS
231-791-2
Name of the chemical
Water, distilled, conductivity or of similar purity H2O
Concentration
N/A
EC/CAS
204-661-8
Name of the chemical
1,4-Dioxan (2021/849)
Concentration
N/A
General Information
Revision date
2021-05-12
Product name
NucleoSpin miRNA (250)
REACH No
see
1.2.2. Uses advised against
not described
Manufacturer Name
MACHEREY-NAGEL GmbH & Co. KG
Emergency telephone
Outside Germany (DE): Call your regional Poisons Information Service or call local Life Saving Service
Icons in SDS
Company Information
company name
MACHEREY-NAGEL GmbH & Co. KG
e-mail address of the competent person responsible for the Safety Data Sheet
sds@mn-net.com (m
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H225, H226, H302, H314, H315, H319, H332, H334, H335, H351, H411, H412
Hazard statements
Code
Statements
H225
Highly Flammable liquid and vapour
Section 2
SECTION 2: Hazards identification
2.0 Classification of the complete product GHS02 GHS07 GHS08 GHS09
Signal word
DANGER Hazard classes/categories H225 Flam. Liq. 2 H226 Flam. Liq. 3 H302 Acute Tox. 4 oral H315 Skin Irrit. 2 H319 Eye Irrit. 2 H334 Resp. Sens. 1 H335 STOT SE 3 H351 Carc. 2 H411 Aquatic Chronic 2 H412 Aquatic Chronic 3 - No hazard class 125 mL MDB GHS02 WARNING Hazard classes/categories H226 Flam. Liq. 3 125 mL ML GHS07 WARNING Hazard classes/categories H302 Acute Tox. 4 oral H412 Aquatic Chronic 3 100 mL MP GHS07 GHS09 WARNING Hazard classes/categories H315 Skin Irrit. 2 H319 Eye Irrit. 2 H411 Aquatic Chronic 2 180 mL MW1 GHS02 WARNING Hazard classes/categories H226 Flam. Liq. 3 50 mL MW2 Do not need labelling as hazardous - No hazard class 250 mL MX GHS02 GHS07 GHS08 DANGER Hazard classes/categories H225 Flam. Liq. 2 H319 Eye Irrit. 2 H335 STOT SE 3 H351 Carc. 2 30 mL RNase-free H 2 O Do not need labelling as hazardous - No hazard class 200 U, Size C, rDNase GHS08 DANGER Hazard classes/categories H334 Resp. Sens. 1 - 125 mL MDB GHS02 125 mL ML GHS07 H412 Harmful to aquatic life with long lasting effects. 100 mL MP GHS07 GHS09 180 mL MW1 GHS02 H226 Flammable liquid and vapour. P210 Keep away from heat/sparks/open flames/hot surfaces. No smoking. 50 mL MW2 Do not need labelling as hazardous - 250 mL MX GHS02 GHS07 GHS08 DANGER H225, H319, H335, H351 Highly flammable liquid and vapour. Causes serious eye irritation. May cause respiratory irritation. Suspected of causing cancer. P201, P210, P261sh, P280sh, P403+233 Obtain special instructions before use. Keep away from heat/sparks/open flames/hot surfaces. No smoking. Avoid breathing dust/vapours. Wear protective gloves/eye protection. Store in a well-ventilated place. Keep container tightly closed. 30 mL RNase-free H 2 O Do not need labelling as hazardous - 200 U, Size C, rDNase GHS08 DANGER H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. P261sh, P342+311 Avoid breathing dust/vapours. If experiencing respiratory symptoms: Call a POISON CENTER/doctor.
2.1 Classification of the substance or mixture
30 mL Buffer for rDNase Do not need labelling as hazardous
2.2 Label elements
According CLP directive inner packages must be only labelled with GHS symbol(s) and product identificator(s) (EU 1272/2008 Annex I - 1.5.1.2). Harmful chemicals/mixtures with signal word: WARNING and highly flammable chemicals/mixtures must not be labelled with H and P phrases until 125 mL (EU 1272/2008 Annex I - 1.5.2). This labelling exemption is NOT valid for sensibilizing substances. 30 mL Buffer for rDNase Do not need labelling as hazardous
2.3 Other hazards
Possible hazards from physicochemical properties In the case of pH values are less than 5 or higher than 9 then it is irritant. Flammable properties. Vapour forms explosive mixtures with air. The property H314 "Causes severe skin burns and eye damage." of some salts is not applicable, because the mixture is buffered to pH >3-4 (see GHS Directive 1272/2008/EC Annex I, chapter 3.2.3.1.2.). For guanidine thiocyanate CAS 593-84-0: The properties H314, H332 "Causes severe skin burns and eye damage. Harmful if inhaled." are not relevant, because the mixture solution is buffered to pH 4-9 (see GHS Directive 1272/2008/EC Annex I, chapter 3.2.3.1.2.). --- Information pertaining to particular risks to human and possible symptoms Cause after oral intake, inhalation of vapours/dust, impairments of health when ingested in small quantities. Kit contains small amounts of enzymes: May cause allergy or asthma symptoms or breathing difficulties if inhaled. Suspected of causing cancer. - Information pertaining to particular risks to the environment Harmful to aquatic life with long lasting effects. Avoid contact of substance/mixture to environment.
PBT Substances
not applicable
vPvB Substances
not applicable