TRIZOL REAGENT

Hazard statements (CLP)

H301, H311, H314, H330, H341, H373, H412

Code

Statements

H301

Toxic if swallowed

Signal word

DANGER

Health hazards

Acute oral toxicity Category 3 Acute dermal toxicity Category 3 Acute Inhalation Toxicity - Dusts and Mists Category 2 Skin Corrosion/Irritation Category 1 B Serious Eye Damage/Eye Irritation Category 1 Specific target organ systemic toxicity (repeated exposure) Category 2 Mutagenicity Mutagenic Category 2

Physical hazards

not hazardous

Hazard statements

H330 - Fatal if inhaled H301 - Toxic if swallowed H311 - Toxic in contact with skin H314 - Causes severe skin burns and eye damage H341 - Suspected of causing genetic defects H373 - May cause damage to organs through prolonged or repeated exposure H412 - Harmful to aquatic life with long lasting effects

Precautionary statements

P301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomiting P301 + P310 - IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower P309 + P311 - IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician P403 + P233 - Store in a well-ventilated place. Keep container tightly closed P280 - Wear protective gloves/protective clothing/eye protection/face protection P284 - Wear respiratory protection P271 - Use only outdoors or in a well-ventilated area P260 - Do not breathe dust/fume/gas/mist/vapors/spray P264 - Wash hands thoroughly after handling P273 - Avoid release to the environment EUH032 - Contact with acids liberates very toxic gas

Potential health effects

Eyes Causes burns. Risk of serious damage to eyes. Corrosive to the eyes and may cause severe damage including blindness. Skin Toxic in contact with skin. Causes burns. Components of the product may be absorbed into the body through the skin. Irritating to skin and mucous membranes. Possible risks of irreversible effects. Inhalation Toxic by inhalation. Causes burns. Ingestion Toxic if swallowed. Ingestion causes burns of the upper digestive and respiratory tracts. Ingestion may cause gastrointestinal irritation, nausea, vomiting and diarrhea. Specific effects Carcinogenic effects Phenol has been classified by the International Agency for Research on Cancer (IARC) as not classifiable as to carcinogenicity to humans (Group 3). Mutagenic effects not applicable Reproductive toxicity not applicable Sensitization not applicable Target Organ Effects Skin Lungs Liver spleen Kidney HMIS Health 3 * Chronic Hazard Flammability 1 Reactivity 0