TRIZOL REAGENT

Hazard statements (CLP)

H302, H312, H314, H332, H335, H341, H373, H412

Code

Statements

H302

Harmful if swallowed

Signal word

DANGER

Health hazards

Acute oral toxicity Category 4 Acute dermal toxicity Category 4 Acute Inhalation Toxicity - Vapors Category 4 Skin corrosion/irritation Category 1 B Serious eye damage/eye irritation Category 1 Specific target organ systemic toxicity (single exposure) Category 3 Specific target organ systemic toxicity (repeated exposure) Category 2 Mutagenicity Mutagenic category 2

Physical hazards

Not Hazardous

Hazard statements

H314 - Causes severe skin burns and eye damage H341 - Suspected of causing genetic defects H373 - May cause damage to organs through prolonged or repeated exposure H412 - Harmful to aquatic life with long lasting effects H302 - Harmful if swallowed H312 - Harmful in contact with skin H332 - Harmful if inhaled H335 - May cause respiratory irritation

Precautionary statements

P301 + P312 - IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing P301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomiting P303 + P361 + P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P310 - Immediately call a POISON CENTER or doctor/physician P308 + P313 - IF exposed or concerned: Get medical advice/attention P273 - Avoid release to the environment P280 - Wear protective gloves/protective clothing/eye protection/face protection

Potential health effects

eyes Causes burns. Risk of serious damage to eyes. Corrosive to the eyes and may cause severe damage including blindness. Skin Causes burns. Possible risk of irreversible effects. Harmful in contact with skin. Irritating to skin and mucous membranes. inhalation Harmful by inhalation. Ingestion Harmful if swallowed. Ingestion causes burns of the upper digestive and respiratory tracts. Ingestion may cause gastrointestinal irritation, nausea, vomiting and diarrhea. Specific effects Carcinogenic effects Phenol has been classified by the International Agency for Research on Cancer (IARC) as not classifiable as to carcinogenicity to humans (Group 3). Mutagenic effects Not Applicable Reproductive toxicity Not Applicable Sensitization Not Applicable Target Organ Effects Skin Lungs Liver spleen Kidney HMIS Health 3 * Chronic Hazard Flammability 1 Reactivity 0