TRIzol Reagent

SECTION 2: Hazards identification

EMERGENCY OVERVIEW **************************** Is a serious health hazard. Overexposure may be fatal. May cause blindness. Acute skin contact danger. Skin contact a principal route of entry. Corrosive to tissue. May cause localized loss of feeling (anesthesia) such that contact may not be sensed. May be rapidly absorbed through the skin in toxic quantities. Acute inhalation danger. May cause substantial respiratory tract injury. May cause respiratory arrest. Acute ingestion danger. Do not induce vomiting. May cause systemic poisoning. May cause convulsions/seizures. May cause death. Overexposure can be dangerous. Get EMERGENCY medical attention. ***************************************************************************** Principal Routes of Entry

Principle Routes of Exposure

Inhalation Yes Skin Yes. Ingestion Yes Effects of Overexposure Acute Effects: From Eye Exposure: May cause lacrimation, or tearing of the eye. May cause conjunctival swelling. May cause loss of sensation in the eye. May cause opacification or clouding of the cornea. May cause corneal ulceration. May cause blindness. From Skin Overexposure: Overexposure may be fatal. Contact may irritate/inflame the skin. Contact may cause a temporary burning sensation in the skin. May cause localized loss of feeling (anesthesia) such that contact may not be sensed. May cause whitening of the skin (blanching) due to reduction in blood flow. May be rapidly absorbed through the skin in toxic quantities. From Inhalation: May cause respiratory tract irritation. May cause substantial respiratory tract injury. May cause respiratory arrest. From Ingestion: May cause severe burns to the mouth. May cause severe burns to the throat. May cause abdominal burning sensation. (Cont.) Other / Systemic Effects May cause systemic poisoning. May cause nausea and/or vomiting. May cause diarrhea. May cause weakness. May cause tinnitus. May cause cyanosis. May cause a loss of the power of muscle coordination (ataxia, dyssynergia). May cause convulsions/seizures. May cause respiratory arrest. May cause unconsciousness/collapse. May cause death. Summary of Medical Conditions Aggravated by Exposure: Renal insufficiency. Hepatic insufficiency. Chronic respiratory pathologies.