Vorinostat

Hazard statements (CLP)

H302, H341, H360, H372, H400, H410

Code

Statements

H302

Harmful if swallowed

2.1 Classification of the substance or mixture

GHS08 Health hazard Muta. 2 H341 Suspected of causing genetic defects. Repr. 1A H360 May damage fertility or the unborn child. STOT RE 1 H372 Causes damage to organs through prolonged or repeated exposure. GHS09 Environment Aquatic Acute 1 H400 Very toxic to aquatic life. Aquatic Chronic 1 H410 Very toxic to aquatic life with long lasting effects. GHS07 (Contd. on page 2) US (Contd. of page 1) Acute Tox. 4 H302 Harmful if swallowed.

2.2 Label elements

The substance is classified and labeled according to the Globally Harmonized System (GHS).

Hazard pictograms

GHS07 GHS08 GHS09

Signal word

Danger

Hazard statements

H302 Harmful if swallowed. H341 Suspected of causing genetic defects. H360 May damage fertility or the unborn child. H372 Causes damage to organs through prolonged or repeated exposure. H400 Very toxic to aquatic life. H410 Very toxic to aquatic life with long lasting effects.

Precautionary statements

P260 Do not breathe dust/fume/gas/mist/vapors/spray. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P301+P312 If swallowed: Call a poison center/doctor if you feel unwell. P405 Store locked up. P501 Dispose of contents/container in accordance with local/regional/national/international regulations.

Classification system

NFPA ratings (scale 0 - 4) Health = 2 0 Fire = 0 2 0 Reactivity = 0 · HMIS-ratings (scale 0 - 4) HEALTH *2 Health = 2 FIRE 0 Fire = 0 REACTIVITY 0 Reactivity = 0

PBT Substances

Not applicable

vPvB Substances

Not applicable US (Contd. on page 3) (Contd. of page 2)