Methotrexate

Hazard statements (CLP)

H301, H301+H311+H331, H311, H315, H319, H331, H340, H360, H372

Code

Statements

H301

Toxic if swallowed

2.1 Classification of the substance or mixture

GHS06 Skull and crossbones Acute Tox. 3 H301 Toxic if swallowed. Acute Tox. 3 H311 Toxic in contact with skin. Acute Tox. 3 H331 Toxic if inhaled. GHS08 Health hazard Muta. 1B H340 May cause genetic defects. Repr. 1A H360 May damage fertility or the unborn child. STOT RE 1 H372 Causes damage to organs through prolonged or repeated exposure. (Contd. of page 1) GHS07 Skin Irrit. 2 H315 Causes skin irritation. Eye Irrit. 2A H319 Causes serious eye irritation.

2.2 Label elements

The substance is classified and labeled according to the Globally Harmonized System (GHS).

Hazard pictograms

GHS06 GHS07 GHS08

Signal word

Danger

Hazard statements

H301+H311+H331 Toxic if swallowed, in contact with skin or if inhaled. H315 Causes skin irritation. H319 Causes serious eye irritation. H340 May cause genetic defects. H360 May damage fertility or the unborn child. H372 Causes damage to organs through prolonged or repeated exposure.

Precautionary statements

P260 Do not breathe dust/fume/gas/mist/vapors/spray. P280 Wear protective gloves/protective clothing/eye protection/face protection. P301+P310 If swallowed: Immediately call a poison center/doctor. P305+P351+P338 If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P405 Store locked up. P501 Dispose of contents/container in accordance with local/regional/national/international regulations.

Classification system

NFPA ratings (scale 0 - 4) Health = 4 0 Fire = 0 4 0 Reactivity = 0 · HMIS-ratings (scale 0 - 4) HEALTH *3 Health = 3 FIRE 0 Fire = 0 REACTIVITY 0 Reactivity = 0 (Contd. of page 2)

PBT Substances

Not applicable

vPvB Substances

Not applicable