Lysis Buffer

Hazard statements (CLP)

H317, H334

Code

Statements

H317

May cause an allergic skin reaction

2.1 Classification of the substance or mixture

The product is not classified as a hazardous substance or mixture according to the Globally Harmonized System (GHS). The product is not classified as a hazardous substance or mixture according to the Globally Harmonized System (GHS). The product is not classified as a hazardous substance or mixture according to the Globally Harmonized System (GHS).

2.2 Label elements

Void Void Void The product is classified and labeled according to the Globally Harmonized System (GHS).

Hazard pictograms

Void Void Void GHS07, GHS08

Signal word

Void Void Void Danger

Hazard statements

Void Void Void H334 - May cause allergy or asthma symptoms or breathing difficulties if inhaled. H317- May cause an allergic skin reaction.

Classification system

NFPA rating (scale 0-4) Health = 0 Fire = 0 Reactivity = 0 WHMIS-rating (scale 0-4) Health = 0 Fire = 0 Reactivity = 0 NFPA rating (scale 0-4) Health = 0 Fire = 0 Reactivity = 0 WHMIS-rating (scale 0-4) Health = 0 Fire = 0 Reactivity = 0 NFPA rating (scale 0-4) Health = 0 Fire = 0 Reactivity = 0 WHMIS-rating (scale 0-4) Health = 0 Fire = 0 Reactivity = 0 NFPA rating (scale 0-4) Health = 0 Fire = 1 Reactivity = 0 28 WHMIS-rating (scale 0-4) Health = 1 Fire = 1 Reactivity = 0

2.3 Other hazards

This mixture has not been tested to determine the overall health hazard; therefore, in accordance with This mixture has not been tested to determine the overall health hazard; therefore, in accordance with Product has been observed to have sensitizing effects 3. Composition/Data on components Chemical characterization: Mixtures Description : Mixture of substances listed below with nonhazardous additions.

Hazardous Ingredients

Void 13 4. First-aid measures General information : No special measure required. After inhalation : Supply fresh air; consult a doctor in case of complaints. After eye contact : Rinse opened eye for several minutes under running water, then consult a doctor. After skin contact : Immediately wash with water and soap and rinse thoroughly. After swallowing : Immediately call a doctor. 5. Firefighting measures Suitable extinguishing agents : CO2, extinguishing powder or water spray. Fight larger fires spray or alcohol resistant foam. Protective equipment : Do not inhale explosion gases or combustion gases. 6. Accidental release measures Personal precautions, protective equipment and emergency procedures : Ensure adequate ventilation. Measures for environmental protection : Dilute with plenty of water. Measures for cleaning/ collecting : Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). 7. Handling and storage Handling Information for safe handling : Keep receptacles tightly sealed. Information about protection against explosions and fires : No special measures required. Conditions for safe storage, including any incompatibilities Void 18 4. First-aid measures General information : No special measure required. After inhalation : Supply fresh air; consult a doctor in case of complaints. After eye contact : Rinse opened eye for several minutes under running water, then consult a doctor. After skin contact : Immediately wash with water and soap and rinse thoroughly. After swallowing : Immediately call a doctor. 5. Firefighting measures Suitable extinguishing agents : CO2, extinguishing powder or water spray. Fight larger fires spray or alcohol resistant foam. Protective equipment : Do not inhale explosion gases or combustion gases. 6. Accidental release measures Personal precautions, protective equipment and emergency procedures : Ensure adequate ventilation. Measures for environmental protection : Dilute with plenty of water. Measures for cleaning/ collecting : Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). 7. Handling and storage Handling Information for safe handling : Keep receptacles tightly sealed. Information about protection against explosions and fires : No special measures required. Conditions for safe storage, including any incompatibilities Void 23 4. First-aid measures General information : No special measure required. After inhalation : Supply fresh air; consult a doctor in case of complaints. After eye contact : Rinse opened eye for several minutes under running water, then consult a doctor. After skin contact : Generally the product does not irritate the skin. After swallowing : Immediately call a doctor 5. Firefighting measures Suitable extinguishing agents : CO2, powder or water spray. Fight larger fires spray or alcohol resistant foam. Protective equipment: Do not inhale explosion gases or combustion gases. 6. Accidental release measures Personal precautions, protective equipment and emergency procedures : Not required. Measures for environmental protection : Dilute with plenty of water. Measures for cleaning/ collecting : Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). 7. Handling and storage Handling Information for safe handling : No special measures required. Information about protection against explosions and fires : No special measures required. Conditions for safe storage, including any incompatibilities CAS: 39450-01-6 proteinase > 1 < 2.5% EINECS: 254-457-8 4. First-aid measures General information : Take affected persons out into the fresh air. Do not leave affected person unattended. After inhalation : Supply fresh air and monitor breathing; call a physician or poison control center immediately. After eye contact : Flush eyes with water or eye wash solution immediately for 15 minutes. Immediate medical attention is required. After skin contact : Immediately wash with excess soap and water. If spilled on clothing, remove all affected clothing. Immediate medical attention is required. After swallowing : Call a physician or poison control center immediately. Only induce vomiting if recommended by medical personnel. If subject is unconscious, do not give anything by mouth. If conscious, rinse mouth with water. 5. Firefighting measures Suitable extinguishing agents : CO2, powder or water spray. Fight larger fires spray or alcohol resistant foam. Protective equipment : Mouth respiratory protective device. Do not inhale explosion gases or combustion gases. 29 6. Accidental release measures Personal precautions, protective equipment and emergency procedures : Ensure adequate ventilation. Wear protective clothing. Measures for environmental protection : Do not allow product to reach sewage system or any water course. Measures for cleaning/ collecting : Ensure adequate ventilation. Absorb liquid components with liquid-binding material. 7. Handling and storage Handling Information for safe handling : Ensure good ventilation/exhaustion at the workplace. Store in cool, dry place in tightly closed receptacles. Information about protection against explosions and fires : Keep ignition sources away-Do not smoke. Conditions for safe storage, including any incompatibilities

Storage

Requirements to be met by storerooms and receptacles : No special measures required. Information about storage in one common storage facility : Not required. Further information about storage conditions : Keep receptacles tightly sealed. 8. Exposure controls and personal protection Additional information about design of technical systems : No further data. Personal protective equipment : General protective and hygienic measures : Keep away from foodstuffs, beverages and feed. Wash hands before breaks and at the end of work. Avoid contact with the eyes and skin. 14 Breathing equipment : Not required. Protection of hands : Protective gloves. Eye protection : Tightly sealed glasses. 9. Physical and chemical properties General Information Form : Fluid Color : Colorless Odor : Not determined. Change in condition Melting point/ Melting range : 0℃ (32℉) Boiling point/ Boiling range : 100℃ (212℉) Flash point : Not applicable. Flammability (solid, gaseous) : Not applicable. Auto igniting : Product is not self-igniting. Danger of explosion : Product does not present an explosion hazard. Upper explosion limit / Upper flammability limit : Not determined. Lower explosion limit / Lower flammability limit : Not determined. Vapour pressure : Not determined. Relative vapour density : Not determined. Relative density : Not determined. Density at 20℃ (68℉) : Not determined. Solubility in / Miscibility with water : Fully miscible. Partition coefficient (n-octanol/water) : Not determined. Viscosity Dynamic : Not determined. Kinematic : Not determined. Water : 99.8% VOC content : 0% pH-value at 20℃ (68℉) : 8.5 10. Stability and reactivity Reactivity : No further relevant information available. Chemical stability Thermal decomposition / conditions to be avoided : No decomposition if used according to specifications. 15 Dangerous reactions : Reacts with strong acids, alkalis and oxidizing agents. Conditions to avoid : No further information available. Incompatible materials : Oxidizing agents Dangerous products of decomposition : Danger of toxic pyrolysis products. Requirements to be met by storerooms and receptacles : No special measures required. Information about storage in one common storage facility : Not required. Further information about storage conditions : Keep receptacles tightly sealed. 8. Exposure controls and personal protection Additional information about design of technical systems : No further data. Personal protective equipment : General protective and hygienic measures : Keep away from foodstuffs, beverages and feed. Wash hands before breaks and at the end of work. Avoid contact with the eyes and skin. 19 Breathing equipment : Not required. Protection of hands : Protective gloves. Eye protection : Tightly sealed glasses. 9. Physical and chemical properties General Information Form : Suspension Color : Black Odor : Not determined. Change in condition Melting point/ Melting range : Undetermined. Boiling point/ Boiling range : Undetermined. Flash point : Not applicable. Flammability (solid, gaseous) : Not applicable. Auto igniting : Product is not self-igniting. Danger of explosion : Product does not present an explosion hazard. Upper explosion limit / Upper flammability limit : Not determined. Lower explosion limit / Lower flammability limit : Not determined. Vapour pressure : Not determined. Relative vapour density : Not determined. Relative density : Not determined. Density at 20℃ (68℉) : 1.016756 g/cm³ (10.19035 lbs/gal). Solubility in / Miscibility with water : Fully miscible. Partition coefficient (n-octanol/water) : Not determined. Viscosity Dynamic : Not determined. Kinematic : Not determined. Water : 0% VOC content : 0% pH-value at 20℃ (68℉) : 8~9 10. Stability and reactivity Reactivity : No further relevant information available. Chemical stability Thermal decomposition / conditions to be avoided : No decomposition if used according to specifications. 20 Dangerous reactions : Reacts with strong acids, alkalis and oxidizing agents. Conditions to avoid : No further information available. Incompatible materials : Oxidizing agents Dangerous products of decomposition : Danger of toxic pyrolysis products. Requirements to be met by storerooms and receptacles : No special measures required. Information about storage in one common storage facility : Not required. Further information about storage conditions : None. 8. Exposure controls and personal protection Control parameters Components with limit values that require monitoring at the workplace : The product does not contains any substances with occupational exposure limit values. Requirements to be met by storerooms and receptacles : Store only in the original receptacle. Information about storage in one common storage facility : Not required. Further information about storage conditions : None. 8. Exposure controls and personal protection Control parameters Components with limit values that require monitoring at the workplace : The product does not contains any substances with occupational exposure limit values.

TOXICOLOGICAL INFORMATION

Acute toxicity LD/LC50 values that are relevant for classification : No data available. Primary irritant effect On the skin : Irritant to skin and mucous membranes. On the eye : Irritating effect. Sensitization: No sensitizing effects known. Additional toxicological information : The product is not subject to classification according to internally calculation methods for preparations. Acute toxicity LD/LC50 values that are relevant for classification : No data available. Primary irritant effect On the skin : Irritant to skin and mucous membranes. On the eye : Irritating effect. Sensitization : No sensitizing effects known. Additional toxicological information : The product is not subject to classification according to internally calculation methods for preparations. Acute toxicity LD/LC50 values that are relevant for classification : No data available. Primary irritant effect On the skin : No irritant effect. On the eye : Irritating effect. Sensitization : No sensitizing effects known. Additional toxicological information : The product is not subject to classification according to internally calculation methods for preparations. Acute toxicity : Based on available data, the classification criteria are not met. Primary irritant effect On the skin : Based on available data, the classification criteria are not met. On the eye: Based on available data, the classification criteria are not met. Sensitization : May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction. Additional toxicological information : The product is not subject to classification according to internally calculation methods for preparations.

ECOLOGICAL INFORMATION

Toxicity Aquatic toxicity : Not harmful to the aquatic environment. Persistence and degradability : Not available. Behavior in environmental systems Bioaccumulative potential : Not known. Mobility in soil : No further relevant information available. Ecotoxical effects Toxicity Aquatic toxicity : Not harmful to the aquatic environment. Persistence and degradability : Not available. Behavior in environmental systems Bioaccumulative potential : Not known. Mobility in soil : No further relevant information available. Ecotoxical effects Toxicity Aquatic toxicity : Not harmful to the aquatic environment. Persistence and degradability : Not available. Behavior in environmental systems Bioaccumulative potential : Not known. Mobility in soil : No further relevant information available. Ecotoxical effects Toxicity Aquatic toxicity : Not harmful to the aquatic environment. Persistence and degradability : Not available. Behavior in environmental systems Bioaccumulative potential : Not known. Mobility in soil : No further relevant information available. Ecotoxical effects

Remarks

Not available Additional ecological information General notes Water hazard class 1 (Self-assessment) slightly hazardous for water. Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system. 13. Disposal considerations Waste treatment methods Recommendation : Disposal should be in accordance with applicable regional, national and local laws and regulations. Uncleaned packagings : Recommendation : Disposal must be made according to official regulations. 16 Recommended cleansing agent : Water, if necessary with cleansing agents. 14. Transportation Information Not available Additional ecological information General notes Water hazard class 1 (Self-assessment) slightly hazardous for water. Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system. 13. Disposal considerations Waste treatment methods Recommendation : Disposal should be in accordance with applicable regional, national and local laws and regulations. Uncleaned packagings : Recommendation : Disposal must be made according to official regulations. Recommended cleansing agent : Water, if necessary with cleansing agents. 21 14. Transportation Information Not available Additional ecological information General notes : Generally not hazardous for water. 13. Disposal considerations Waste treatment methods Recommendation : Disposal should be in accordance with applicable regional, national and local laws and regulations. Uncleaned packagings : Recommendation : Disposal must be made according to official regulations. 26 Recommended cleansing agent : Water, if necessary with cleansing agents. 14. Transportation Information Not available Additional ecological information General notes : Generally not hazardous for water. 13. Disposal considerations Waste treatment methods Recommendation : Disposal should be in accordance with applicable regional, national and local laws and regulations. Uncleaned packagings : Recommendation : Disposal must be made according to official regulations. Recommended cleansing agent : Water, if necessary with cleansing agents. 14. Transportation Information

UN Number

Not regulated as a dangerous good UN proper shipping name : Not regulated as a dangerous good Transport hazard class(es) : Not regulated as a dangerous good Packing group : Not regulated as a dangerous good Not regulated as a dangerous good UN proper shipping name : Not regulated as a dangerous good Transport hazard class(es) : Not regulated as a dangerous good Packing group : Not regulated as a dangerous good Not regulated as a dangerous good UN proper shipping name : Not regulated as a dangerous good Transport hazard class(es) : Not regulated as a dangerous good Packing group : Not regulated as a dangerous good Not regulated as a dangerous good UN proper shipping name : Not regulated as a dangerous good Transport hazard class(es) : Not regulated as a dangerous good Packing group : Not regulated as a dangerous good 32

Environmental hazards

Not regulated as a dangerous good Special precautions for user Remarks : Not dangerous goods in the meaning of ADR/RID, ADN, IMDG-Code, ICAO/IATA-DGR 15. Regulatory information This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and establish relationship. Not regulated as a dangerous good Special precautions for user Remarks : Not dangerous goods in the meaning of ADR/RID, ADN, IMDG-Code, ICAO/IATA-DGR 15. Regulatory information This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and establish relationship. Not regulated as a dangerous good Special precautions for user Remarks : Not dangerous goods in the meaning of ADR/RID, ADN, IMDG-Code, ICAO/IATA-DGR 15. Regulatory information This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and establish relationship. Not regulated as a dangerous good Special precautions for user Remarks : Not dangerous goods in the meaning of ADR/RID, ADN, IMDG-Code, ICAO/IATA-DGR 15. Regulatory information This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and establish relationship.

Further information

If you want further information, please contact TANBead sales representative (Tel: +886-3-3167568) 17 MSDS-No. : BF2C 2. If you want further information, please contact TANBead sales representative (Tel: +886-3-3167568) 22 MSDS-No. : EB-M665 2. If you want further information, please contact TANBead sales representative (Tel: +886-3-3167568) 27 MSDS-No. : B161 2. If you want further information, please contact TANBead sales representative (Tel: +886-3-3167568)

Other hazards

This mixture has not been tested to determine the overall health hazard; therefore, in accordance with

Additional information

No further data Personal protective equipment 24 General protective and hygienic measures : Keep away from foodstuffs, beverages and feed. Wash hands before breaks and at the end of work. Avoid contact with the eyes and skin. Breathing equipment : Not required. Protection of hands : Protective gloves. Eye protection : Not required. 9. Physical and chemical properties General Information Form : Fluid Color : Colorless Odor : Not determined. Change in condition Melting point/ Melting range : 0℃ (32℉) Boiling point/ Boiling range : 100℃ (212℉) Flash point : Not applicable. Flammability (solid, gaseous) : Not applicable. Auto igniting : Product is not self-igniting. Danger of explosion : Product does not present an explosion hazard. Upper explosion limit / Upper flammability limit : Not determined. Lower explosion limit / Lower flammability limit : Not determined. Vapour pressure : Not determined. Relative vapour density : Not determined. Relative density : Not determined. Density at 20℃ (68℉) : Not determined. Solubility in / Miscibility with water : Fully miscible. Partition coefficient (n-octanol/water) : Not determined. Viscosity Dynamic : Not determined. Kinematic : Not determined. Water : 99.8% VOC content : 0% pH-value at 20℃ (68℉) : 8.5 10. Stability and reactivity 25 Reactivity : No further relevant information available. Chemical stability Thermal decomposition / conditions to be avoided : No decomposition if used according to specifications. Dangerous reactions : No dangerous reactions known. Conditions to avoid : No further information available. Incompatible materials : No further information available. Dangerous products of decomposition : No dangerous decomposition products known. No further data Personal protective equipment General protective and hygienic measures : The usual precautionary measures are to be adhered to when handling chemicals. Immediately remove all soiled and contaminated clothing. Do not inhale gases/fumes/aerosols. Wash hands before breaks and at the end of work. Avoid contact with the eyes and skin Breathing equipment : Tightly fitting safety goggles. Protection of hands : Protective gloves. 30 Eye protection : Not required if room is well-ventilated. 9. Physical and chemical properties General Information Form : Fluid Color : Colorless Odor : Not determined. Change in condition Melting point/ Melting range : Not applicable. Boiling point/ Boiling range : Not applicable. Flash point: Not applicable. Flammability (solid, gaseous) : Not applicable. Auto igniting : Product is not self-igniting. Danger of explosion : Product does not present an explosion hazard. Upper explosion limit / Upper flammability limit : Not determined. Lower explosion limit / Lower flammability limit : Not determined. Vapour pressure : Not determined. Relative vapour density : Not determined. Relative density : Not determined. Density at 20℃ (68℉) : 1.126 g/cm³ (9.396925 lbs/gal). Solubility in / Miscibility with water : Fully miscible. Partition coefficient (n-octanol/water) : Not determined. Viscosity Dynamic : Not determined. Kinematic : Not determined. Water : Not determined. VOC content : Not determined. pH-value at 20℃ (68℉) : 7.5 10. Stability and reactivity Reactivity : No further relevant information available. Chemical stability Thermal decomposition / conditions to be avoided : No decomposition if used according to specifications. Dangerous reactions : No dangerous reactions known. Conditions to avoid : No further information available. Incompatible materials : No further information available. Dangerous products of decomposition : Carbon monoxide and carbon dioxide. 31

Precautionary statements

P101 - If medical advice is needed, have product container or label at hand. P102 - Keep out of reach of children. P261 - Avoid breathing dust/fume/gas/mist/vapors/spray. P280 - Wear protective gloves/protective clothing/eye protection/face protection. P284 – [In case of inadequate ventilation] wear respiratory protection. P304 + P340 - If Inhaled: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P342 + P311 - If experiencing respiratory symptoms: Call a poison center or doctor/physician.