CytodetectTM kit

Hazard statements (CLP)

H300, H302, H315, H317, H318, H319, H332, H335, H351

Code

Statements

H300

Fatal if swallowed

2.1 Classification of the substance or mixture

There are no reported further health hazards for the product in the current formulation and applications. Only reagents A, B, C, E and G contain dangerous substances in amounts that need to be hazard labeled according to EC Regulation No. 1272/2008. All other components of the product contain substances that may be hazardous when available in significant amounts and should be treated as potentially biohazardous. SDS-IQP-366 Version 1/ Revised Date: 17July2015 Kit Components: Reagent A: Stimulation reagent (A); Reagent B: Stimulation reagent (B); Reagent C: Accumulation reagent (C); Reagent D: Washing Solution (10xD); Reagent E: Fixative solution (E); Reagent F: Permeabilization buffer (10xF); Reagent G: Permeabilization reagent (100xG)

Hazard pictograms

Reagent A Reagent B: Reagent C: Reagent D: NOT APPLICABLE Reagent E: Reagent F: NOT APPLICABLE Reagent G:

Signal word

Reagent A: WARNING Reagent B: WARNING Reagent C: DANGER Reagent D: NOT APPLICABLE Reagent E: DANGER Reagent F: NOT APPLICABLE Reagent G: DANGER

Hazard statements

Reagent A Reagent B Reagent C Reagent D Reagent E Reagent F Reagent G H315 Causes H302 H300 Fatal None apply H302 None apply H319 Causes skin irritation Harmful if if Harmful if serious eye swallowed irritation H319 Causes H315 H335 May serious eye Causes skin cause irritation respiratory irritation H335 May H317 May cause cause an respiratory allergic skin irritation reaction H318 Causes serious eye damage H332 Harmful if inhaled H335 May cause respiratory irritation H351 Suspected of causing cancer SDS-IQP-366 Version 1/ Revised Date: 17July2015 with if on soap to a to easy wash position for If call or + rinsing If If keep center + If cautiously for of + gently + plenty in Reagent P301 swallowed, immediately poison doctor/physician P305 P338 rinse water minutes. contact present do. P310 P351 in lenses, and Continue P350 P302 skin, with and P304 inhaled, fresh at comfortable breathing. water P340 remove and rest G eyes, several Remove a + air F apply Reagent None with on to a P310 center P351 in several Remove lenses, and P350 if call easy wash of If or + If soap E Continue eyes, + gently plenty water 9 of + + If cautiously for 1 Reagent P301 swallowed, immediately poison doctor/physician P305 P338 rinse water minutes. contact present do. rinsing. P302 skin, with and Page D apply Reagent None a Reagent P301 swallowed, immediately poison doctor/physician If call or Date: 17July2015 P310 center Date: C + (GHS-US): P310 center 1/ a Version Reagent P301 swallowed, immediately poison doctor/physician call If or B + P350 + gently P351 in + If cautiously minutes. if contact SDS-IQP-366 If soap + on wash of eyes, for present to rinsing. do. Precautionary Reagent P302 skin, with and P305 P338 rinse with several Remove lenses, and Continue A plenty water water easy / in on G not skin Reagent P261 breathing dust/fume/gas/ mist/vapors/spray / gloves clothing P262 eyes, clothing P280 protective protective eye face get or / Avoid Do on Wear protection protection / gloves clothing / F Wear protection protection Reagent P280 protective protective eye face / in on away sparks / hot mist get or / Keep heat flames protection E / no dust spray gloves clothing – 9 not skin gas / of Avoid / Wear Do on 1 Reagent P210 from open surfaces smoking P261 breathing fume vapours P280 protective protective eye face P262 eyes, clothing Page / gloves clothing / D Wear protection Reagent P280 protective protective eye face in on hands after get or 17July2015 C not skin Do on Wash Date: Reagent P262 eyes, clothing P264 thoroughly handling Revised 1/ hands after mouth Version B Wash Rinse Reagent P264 thoroughly handling P330 General protection / SDS-IQP-366 / gloves clothing / A Wear Reagent P280 protective protective eye face

2.3 Other hazards

All reagents should be handled in accordance with good laboratory practices using appropriate precautions. In addition, handle all patient samples with appropriate precautions as described in “Biosafety in Microbial and Biomedical Laboratories”, 2nd ed., 1988. HHS Publication No. (CDC) 88-8395, Centers for Disease Control. There are no reported further health hazards for the product in the current formulation and applications. The product contain substances that may be hazardous when available in significant amounts and should be treated as potentially biohazardous. No toxic effects are to be expected when the product is handled appropriately. The product may enter the body through inhalation, ingestion, skin contact and eye contact. Sodium azide forms explosive compounds with heavy metals. Components of this product contain azide < 0,1% (w/v). Repeated contact of these components with lead and copper, commonly found in plumbing drains, should be avoided as this may result in the buildup of shock-sensitive compound. On disposal, flush with large amounts of water to prevent azide build-up.