General Information
Revision date
2014-10-07
Product name
(626) 459-5255
Product Synonyms
(-)-17-Allyl-4,5a-epoxy-3, 14-dihydroxymorphinan-6-one hydrochloride
CAS No.
357-08-4
1.2.1 Relevant identified uses
Rx Only. Naloxone hydrochloride injection
Manufacturer Name
International Medication Systems, Limited (IMS)
Icons in SDS
Company Information
company name
International Medication Systems, Limited (IMS)
GHS Information
Signal word
Warning
Hazard Codes
Hazard statements (CLP)
H302
Hazard statements
Code
Statements
H302
Harmful if swallowed
Section 2
Hazard statements
Excessive doses of naloxone hydrochloride in postoperative patients may result in significant reversal of analgesia and may cause agitation. MSDS Name Naloxone Hydrochloride Injection USP Approved By/Date iby Page | of 7 qiof/t MATERIAL SAFETY DATA SHEET
Potential health effects
The following adverse events have been associated with the use of naloxone hydrochloride in postoperative patients: hypotension, hypertension, ventricular tachycardia and fibrillation, dyspnea, pulmonary edema, and cardiac arrest. Death, coma, and encephalopathy have been reported as sequelae of these events. Excessive doses of naloxone hydrochloride in postoperative patients may result in significant reversal of analgesia and may cause agitation. Adverse events associated with the postoperative use of naloxone hydrochloride include disorders of the cardiac, gastrointestinal, nervous system, psychiatric, respiratory, skin and subcutaneous tissue or vascular.
Hazard categories
Not available
2.1 Classification of the substance or mixture
Unknown
EU Classification
Directives 64/548/EEC (substances) or | R22 1999/45/EC (mixtures)
