17i Printing Ink

Hazard statements (CLP)

H225, H302, H319, H370

Code

Statements

H225

Highly Flammable liquid and vapour

SECTION 2: Hazards identification

Classification of the Substance or Mixture Flammable Liquids, Category 2 Acute Toxicity: Oral, Category 4 Serious Eye Damage/Eye Irritation, Category 2 Specific Target Organ Toxicity (single exposure), Category 1

Signal word

Danger

Hazard statements

H225 - Highly flammable liquid and vapor. H302 - Harmful if swallowed. H319 - Causes serious eye irritation. H370 - Causes damage to organs

Precautionary statements

P233 - Keep container tightly closed. P210 - Keep away from P280 - Wear protective heat/sparks/open flames/hot surfaces. - No smoking. gloves/protective clothing/eye protection/face protection. P240 - Ground/bond container and receiving equipment. P241 - Use explosion-proof electrical/ventilating/lighting/.../ equipment. P243 - Take precautionary measures against static discharge. P242 - Use only non-sparking tools. P264 - Wash hands thoroughly after handling. P270 - Do not eat, drink or smoke when using this product. P260 - Do not breathe dust/fume/gas/mist/vapors/spray.

Response

P370+378 - In case of fire, use ... to extinguish. P303+361+353 - IF ON water/shower. SKIN (or hair): Remove/take off immediately all contaminated clothing. Rinse skin with P301+312 - IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P330 - Rinse mouth. P305+351+338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+313 - If eye irritation persists, get medical advice/attention. P321 - Specific treatment see ... on this label.

Storage

P403+235 - Store in cool/well-ventilated place. P501 - Dispose of contents/container to ... P405 - Store locked up.

Potential health effects

Prolonged or repeated skin contact may cause defatting and dermatitis. Animal studies have reported that fetal effects/abnormalities may occur when maternal toxicity is seen. Chronic inhalation may cause effects similar to those of acute inhalation. Chronic overexposure to vapors may cause lung damage. Chronic: 2.3.1 Inhalation Causes respiratory tract irritation. Inhalation of vapors may cause drowsiness and dizziness. May cause central nervous system effects such as nausea and headache. Neurobehavioural effects of exposure to MEK (200 ppm for 4 hrs) were studied with 137 volunteers. There were no statistically significant effects observed in biochemical, psychomotor, sensorimotor and psychological tests. Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. May cause narcotic effects in high concentration. Causes upper respiratory tract irritation. 2.3.2 Skin Contact May be absorbed through the skin in harmful amounts. Repeated or prolonged exposure may cause drying and cracking of the skin. Only one human case of skin sensitization was located. Negative results were obtained in an animal test; MEK did not produce skin sensitization in the mouse ear thickness test. May cause irritation with pain and stinging, especially if the skin is abraded. Isopropanol has a low potential to cause allergic skin reactions; however, rare cases of allergic contact dermatitis have been reported. Dermal absorption has been considered toxicologically insignificant. The cases of deep coma associated with skin contact are thought to be a consequence of gross isopropanol vapor inhalation in rooms with inadequate ventilation, rather than being attributable to percutaneous absorption of isopropanol per se. 2.3.3 Eye Contact Causes eye irritation. Vapors may cause eye irritation. Animal evidence suggests that MEK is a moderate to severe eye irritant. Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury. May cause transient corneal injury. In the eyes of a rabbit, 0.1 ml of a rabbit, 0.1 ml of 70% isopropyl alcohol caused conjunctivitis, isopropyl alcohol caused conjun ctivitis, iritis, and corneal opacity. 2.3.4 Ingestion May cause irritation of the digestive tract. Possible aspiration hazard. May cause central nervous system depression. Animal evidence suggests that MEK can be aspirated (inhaled) into the lungs during ingestion or vomiting. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause kidney damage. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal. The probable oral lethal dose in humans is 240 ml (2696 mg/kg), but ingestion of only 20 ml (224 mg/kg) has, but in gestion of only 20 ml (224 mg/kg) has caused poisoning.

2.1 Classification of the substance or mixture

Flammable Liquids, Category 2 Acute Toxicity: Oral, Category 4 Serious Eye Damage/Eye Irritation, Category 2 Specific Target Organ Toxicity (single exposure), Category 1