Indu-Crete Part B

Hazard statements (CLP)

H315, H317, H320, H332, H334, H335, H351, H373

Code

Statements

H315

Causes skin irritation

2.1 Classification of the substance or mixture

Acute Tox. 4 (Inhalation - mist) Acute toxicity Eye Dam./Irrit. 2B Serious eye damage/eye irritation Skin Corr./Irrit. 2 Skin corrosion/irritation Skin Sens. 1B Skin sensitization Resp. Sens. 1 Respiratory sensitization Carc. 2 Carcinogenicity

Contains

4,4’-Diphenylmethane Diisocyanate

Signal word

Danger

Hazard statements

H320 Causes eye irritation. H315 Causes skin irritation. H332 Harmful if inhaled. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H317 May cause an allergic skin reaction. H335 May cause respiratory irritation. H351 Suspected of causing cancer. H373 May cause damage to organs (Olfactory organs) through prolonged or repeated exposure (inhalation).

Prevention

P2 0 Wear protective gloves/protective clothing/eye protection/face protection. P271 se only outdoors or in a well-ventilated area. P260 Do not breathe dust/gas/mist/vapors. P201 Obtain special instructions before use. P261 Avoid breathing mist. P202 Do not handle until all safety precautions have been read and understood. P2 4 In case of inadequate ventilation ear respiratory protection. P272 Contaminated work clothing should not be allowed out of the workplace. P264 Wash with plenty of water and soap thoroughly after handling.

Response

P312 Call a POISON CENTER or doctor/physician if you feel unwell. P305+P351+P33 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P308+P311 IF exposed or concerned: Call a POISON CENTER or doctor/physician. P314 Get medical advice/attention if you feel unwell. P303+P352 IF ON SKIN (or hair): Wash with plenty of soap and water. P333+P311 If skin irritation or rash occurs: Call a POISON CENTER or doctor/ physician. P362+P364 Take off contaminated clothing and wash before reuse. P332+P313 If skin irritation occurs: get medical advice/attention. P337+P311 If eye irritation persists: Call a POISON CENTER or doctor/physician.

Principle Routes of Exposure

Routes of entry for solids and liquids include eye and skin contact, ingestion and inhalation. Routes of entry for gases include inhalation and eye contact. Skin contact may be a route of entry for liquefied gases. Acute toxicity - Inhalation of MDI vapors may cause irritation of the mucous membranes of the nose, throat or breathlessness, chest discomfort, difficult breathing and reduced pulmonary function. Airborne overexposure well above the PEL may result additionally in eye irritation, headache, chemical bronchitis, asthma-like findings or pulmonary edema. Isocyanates have also been reported to cause hypersensitivity pneumonitis, which is characterized by flu-like symptoms, the onset of which may be delayed. Gastrointestinal symptoms include nausea, vomiting and abdominal pain. Irritation - Eye contact with isocyanates may result in conjunctival irritation and mild corneal opacity. Skin contact may result in dermatitis, either irritative or allergic. Repeated dose toxicity - Information on MDI: Results from a lifetime inhalation study in rats indicate that MDI aerosol was carcinogenic at 6mg/m3, the highest dose tested. This is well above the recommended TLV of 5 ppb (0.05 mg/m3).Only irritation was noted at the lower concentration of 0.2 and 1 mg/m3. No birth defects or teratogenic effects were reported in a teratology study with rats exposed to 1, 4, and 12 mg/m3 polymeric MDI for 6 hr/day on days 6-15 of gestation. Embryotoxicity and fetotoxicity was reported at the top dose in the presence of maternal toxicity. Medical conditions aggravated by overexposure - The isocyanates component is a respiratory sensitizer. It may cause allergic reaction leading to asthma-like spasms of the bronchial tubes and difficulty in breathing. Persons with history of respiratory disease or hypersensitivity should not be exposed to this product. An animal study indicated that MDI may induce respiratory hypersensitivity following dermal exposure. Medical supervision of all employees who handle or come into contact with isocyanates is recommended. Preemployment and periodic medical examinations with respiratory function tests (FEV, FVC as a minimum) are suggested. Persons with asthmatic conditions, chronic bronchitis, other chronic respiratory diseases, recurrent eczema or pulmonary sensitization should be excluded from working with isocyanates. Once a person is diagnosed as having pulmonary sensitization (allergic asthma) to isocyanates, further exposure is not recommended. Contact may aggravate pulmonary disorders. General Information: This product contains no listed carcinogens according to IARC, ACGIH, NTP and/or OSHA in concentrations of 0.1 percent or greater. Prolonged contact may result in chemical burns and permanent damage. Repeated or prolonged contact causes sensitization, asthma and eczemas. Read the entire SDS for a more thorough evaluation of the hazards.