PolyCYPs Enzyme Reagent Kit

Hazard statements (CLP)

H301, H314, H318, H319, H334, H335, H412

Code

Statements

H301

Toxic if swallowed

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture

Recombinant crude enzyme preparation from E. coli Respiratory sensitization (Category 1), H334 Not a hazardous substance or mixture according to Potassium Phosphate Monobasic Regulation (EC) No. 1272/2008. Not a hazardous substance or mixture according to Potassium Phosphate Dibasic Trihydrate Regulation (EC) No. 1272/2008. Not a hazardous substance or mixture according to Magnesium Chloride Hexahydrate Regulation (EC) No. 1272/2008. Not a hazardous substance or mixture according to Glycyl-Glycine Regulation (EC) No. 1272/2008. Not a hazardous substance or mixture according to Benzonase Nuclease Regulation (EC) No. 1272/2008. Skin corrosion (Sub-category 1B), H314 Serious eye damage (Category 1), H318 Tris(2-carboxyethyl)phosphine hydrochloride Specific target organ toxicity – single exposure (Category 3), Respiratory system, H335 Acute oral toxicity (Category 3), H301 PMSF Protease Inhibitor Skin corrosion/irritation (Category 1B), H314 Serious eye damage/eye irritation (Category 1), H314 Not a hazardous substance or mixture according to D-Glucose 6-phosphate disodium salt hydrate Regulation (EC) No. 1272/2008. β-Nicotinamide adenine dinucleotide Eye irritation (Category 2), H319 phosphate sodium salt hydrate Glucose-6-phosphate Dehydrogenase, from baker's yeast Respiratory sensitization (Category 1), H334 (S. cerevisiae) Not a hazardous substance or mixture according to 2-Hydroxypropyl-β-cyclodextrin Regulation (EC) No. 1272/2008. Bosentan hydrate Long-term (chronic) aquatic hazard (Category 3), H412

Precautionary statements

Word H334 – May cause allergy P261 – Avoid breathing dust. Recombinant crude or asthma symptoms or P284 – Wear respiratory protection. enzyme preparation Danger breathing difficulties if P501 – Dispose of contents/container to from E. coli inhaled. an approved waste disposal plant. P261 – Avoid breathing mist or vapours. P271 – Use only outdoors or in a well ventilated-area. P280 – Wear protective gloves/protective clothing/eye protection/face protection. P303 + P361 + P353 – IF ON SKIN (or H314 – Causes severe skin hair): Take off immediately all burns and eye damage. contaminated clothing. Rinse skin with Tris(2-carboxyethyl) H318 – Causes Serious eye water. phosphine Danger damage. P304 + P340 + P310 – IF INHALED: hydrochloride H335 – May cause Remove person to fresh air and keep respiratory irritation. comfortable for breathing. Immediately call a POISON CENTRE or doctor. P305 + P351 + P338 – IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P280 – Wear protective gloves/protective clothing/eye protection/face protection. P260 – Do not breathe H301 – Toxic if swallowed. dust/fume/gas/mist/vapours/spray PMSF Protease Danger H314 – Causes severe skin P270 – Do not eat, drink or smoke when Inhibitor burns and eye damage. using this product. P264 – Wash hands thoroughly after handling. P304 + P340 + P310 – IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTRE or doctor. P301 + P310 + P330 + P331 – IF SWALLOW: rinse mouth. Do NOT induce vomiting. Immediately call a POISON CENTRE/doctor. P305 + P351 + P338 – IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P303 + P361 + P353 + P311 – IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. Call a POISON CENTRE or doctor. P363 – Wash contaminated clothing before reuse. P501 – Dispose of contents/container to an approved waste disposal plant. P280 – Wear eye protection/face protection. P305 + P351 + P338 – IF IN EYES: Rinse β-Nicotinamide cautiously with water for several adenine dinucleotide H319 – Causes serious eye Warning minutes. Remove contact lenses, if phosphate sodium irritation. present and easy to do. Continue salt hydrate rinsing. P337 + P313 – If eye irritation persists: Get medical advice/attention. Glucose-6-phosphate H334 – May cause allergy P261 – Avoid breathing dust. Dehydrogenase, from or asthma symptoms or P284 – Wear respiratory protection. Danger baker's yeast (S. breathing difficulties if P501 – Dispose of contents/container to cerevisiae) inhaled. an approved waste disposal plant. P261 – Avoid breathing 2-Hydroxypropyl-β- dust/fume/gas/mist/vapour/spray. None Not classified cyclodextrin P262 – Do not get in eyes, on skin, or on clothing. P273 – Avoid release to the H412 – Harmful to aquatic environment. Bosentan hydrate None life with long lasting effects. P501 – Dispose of contents/container to an approved waste disposal plant.

2.3 Other hazards

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.