Piperacillin and Tazobactam for Injection

SECTION 2: Hazards identification

GHS Classification Emergency Overview Piperacillin and Tazobactam for Injection is a powder containing a combination of the semisynthetic antibiotic piperacillin sodium and tazobactam sodium, a β-lactamase inhibitor. In clinical use, it is intended for intravenous administration for the treatment of susceptible infections. In the workplace, this material should be considered potentially irritating to the skin, eyes and respiratory tract, and a potential sensitizer which may induce allergic reactions in persons known to be sensitized to penicillins and cephalosporins. Based on clinical use, possible target organs include the gastrointestinal system, skin, hematopoietic system, and liver. U.S. OSHA GHS Classification

Hazard categories

Not Classified Eye Damage/Irritation 2B Sensitization – Skin 1 Sensitization – Respiratory 1 STOT - RE 2

Signal word

Danger

Hazard statements

Causes eye irritation May cause an allergic skin reaction May cause allergic or asthmatic symptoms or breathing difficulties if inhaled May cause damage to organs through prolonged or repeated exposure. 1 continued

Prevention

Do not breathe dust/vapors/spray In case of inadequate ventilation, wear respiratory protection Wear protective gloves Wash hands thoroughly after handling Contaminated work clothing must not be allowed out of the workplace

Response

Get medical attention if you feel unwell. IF INHALED: If breathing is difficult, remove person to fresh air and keep comfortable for breathing. If experiencing respiratory symptoms: Call a doctor. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists, get medical attention. IF ON SKIN Wash with plenty of water. If skin irritation or rash occurs Get medical advice/attention. Wash contaminated clothing before reuse.