General Information
Revision date
2014-06-02
Product name
Imipenem and Cilastatin for Injection
Product Synonyms
Imipenem (N-formimidoylthienamycin monohydrate; (5R,6S)-6-[(R)-1- Hydroxyethyl]-3-(2-iminomethylaminoethylthio)-7-oxo-1-azabicyclo[3.2.0]hept-2-
Manufacturer Name
Hospira, Inc
Emergency telephone
North America 800-424-9300;
Icons in SDS
Company Information
company name
Hospira, Inc
GHS Information
Signal word
Danger
Section 2
SECTION 2: Hazards identification
GHS Classification Emergency Overview Imipenem and Cilastatin for Injection is a powder containing imipenem (a thienamycin antibiotic) and cilastatin sodium (the inhibitor of the renal dipeptidase, dehydropeptidase I). It is a broad-spectrum antibacterial agent given by intravenous administration. In the workplace, this material should be considered potentially irritating to the skin, eyes and respiratory tract, and a potential sensitizer which may induce allergic reactions in persons known to be sensitized to penicillins and cephalosporins. Based on clinical use, possible target organs include the gastrointestinal system, skin, hematopoietic system, and liver. U.S. OSHA GHS Classification
Hazard categories
Not Classified Eye Damage / Irritation 2B Sensitization – Skin 1 Sensitization – Respiratory 1 STOT – RE 2
Signal word
Danger
Hazard statements
Causes eye irritation May cause an allergic skin reaction May cause allergy or asthma symptoms or breathing difficulties if inhaled May cause damage to organs through prolonged or repeated exposure 1 continued
Prevention
Do not breathe vapor or spray Wear protective gloves/protective clothing/eye protection/face protection Wash hands after handling In case of inadequate ventilation, wear respiratory protection Contaminated work clothing must not be allowed out of the workplace Wash hands thoroughly after handling
Response
If exposed or concerned: Get medical advice/attention if you feel unwell. IF INHALED: If breathing is difficult, remove person to fresh air and keep comfortable for breathing. If experiencing respiratory symptoms: Call a doctor. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists, get medical attention. IF ON SKIN Wash with plenty of water. If skin irritation or rash occurs Get medical advice/attention. Wash contaminated clothing before reuse.
