TOOTHPASTE

SECTION 2: Hazards identification

Chemical Name CAS EINECS

Contains

Potassium nitrate 7757-79-1 231-818-8 3% Sodium fluoride 7681-49-4 231-667-8 1% Carbomer 1% Poloxamer 407 9003-11-6 4% 1,2-propanediol 57-55-6 200-338-0 40% Deionized water 7732-18-5 50% Poly vinylpyrrolidone 0.5% Menthol 0.5% 3. PHYSICAL & CHEMICAL CHARACTERISTICS PHYSICAL PROPERTIES RELATIVE VAPOR DENSITY Not EVAPORATION RATE Not Available (air = 1): Available (BuAc =1): SPECIFIC GRAVITY: > 1 MELTING/FREEZING Not Available POINT: SOLUBILITY IN WATER: Miscible BOILING POINT: Not Available VAPOR PRESSURE, mm Hg @ Not pH: ~4 20°C: Available COEFFICIENT OF OIL/WATER DISTRIBUTION (PARTITION Not Available COEFFICIENT) PHYSICAL STATE, APPEARANCE Translucent to waxy gel with odor characteristic of AND COLOR flavoring ingredients. HOW TO DETECT THIS SUBSTANCE (warning properties): The appearance and odor of this product can act as warning properties in the event of an accidental release CHEMICAL PROPERTIES ODOR THRESHOLD: Not Available FLASH Not determined AUTOIGNITION Not determined POINT: TEMPERATURE: FLAMMABLE LIMITS (in air by volume, %): Lower: Not Upper: Not determined determined

TOXICOLOGICAL INFORMATION

TOXICITY DATA: The following toxicity data are available for this product. The following data are available for a water conditioner component: LD50= 12,600 mg/kg Oral-Rat 4420 mg/kg Intraperitoneal-Rat 100 mg/kg Subcutaneous-Rat 4090 mg/kg Oral-Mouse: 8982 mg/kg Intraperitoneal-Mouse 91 mg/kg Subcutaneous-Mouse 4250 mg/kg Intravenous-Mouse 53 g/kg Intravenous-Rabbit, adult 7750 mg/kg Oral-Guinea Pig, adult The following data are available for a second water conditioner component: Skin-Human 500 mg/7D Mild irritation effects Skin-Human 104 mg/3D-I Moderate irritation effects Skin-Man 10%/2D Eye effects-Rabbit, adult 100 mg Mild irritation effects Eye effects-Rabbit, adult 500 mg/24H Mild irritation effects DNA Inhibition-Mouse-Subcutaneous 8000 mg/kg Cytogenetic Analysis-Mouse-Subcutaneous 8000 mg/kg Cytogenetic Analysis-Hamster: fibroblast 32 g/L Intraperitoneal-Mouse TDLo 100 mg/kg (15D preg) Teratogenic effects Intraperitoneal-Mouse TDLo 100 mg/kg (11D preg) Reproductive effects Oral-Child TDLo 79 g/kg/56W-I Central nervous system effects, BRN Parenteral-Infant TDLo 10 g/kg/3D-C Systemic effects Oral-Rat LD50:20 g/kg Intraperitoneal-Rat LD50:6660 mg/kg Subcutaneous-Rat LD50:22,500 mg/kg Intravenous-Rat LD50:6423 mg/kg Intramuscular-Rat LD50:14 g/kg Oral-Mouse LD50:22 g/kg Intraperitoneal-Mouse LD50:9718 mg/kg Subcutaneous-Mouse LD50:17,370 mg/kg Intravenous-Mouse LD50:6630 mg/kg SUSPECTED CANCER AGENT: The following table summarizes the carcinogenicity listing for the components of this product. “NO” indicates that the substance is not considered to be, or suspected to be, a carcinogen by the listed agency, see section 16 for definition of other ratings. CHEMICAL IARC NTP NIOSH ACGIH OSHA CA PROP 65 Water Conditioners No Whitening Agents 3 No A3 No IRRITANCY OF PRODUCT: This product can be mildly irritating to contaminated tissue. Prolonged exposure can lead to tissue damage. SENSITIZATION TO THE PRODUCT: This product has not been reported to be a sensitizer. TOXICOLOGICAL SYNERGISTIC PRODUCTS: None. REPRODUCTIVE TOXICITY INFORMATION: Listed below is information concerning the effects of this product and its components on the human reproductive system. Mutagenicity: When used as directed, this product is not expected to produce mutagenic effects in humans. Embryotoxicity: When used as directed, this product is not expected to produce embryotoxic effects in humans.

Teratogenic Effects

When used as directed, this product is not expected to produce teratogenic effects in humans. Reproductive Toxicity: When used as directed, this product is not expected to produce reproductive toxicity in humans. A mutagen is a chemical that causes permanent changes to genetic material (DNA) such that the changes will propagate through generational lines. An embryotoxin is a chemical that causes damage to a developing embryo (i.e. within the first eight weeks of pregnancy in humans), but the damage does not propagate across generational lines. A teratogen is a chemical that causes damage to a developing fetus, but the damage does not propagate across generational lines. A reproductive toxin is any substance that interferes in any way with the reproductive process. BIOLOGICAL EXPOSURES INDICES (BEIs): There are no BEI’s established for any component of this product at this time. 5. STABILITY and REACTIVITY CHEMICAL STABILITY Stable under normal circumstances of use and handling. CONDITIONS TO AVOID Avoid contact with incompatible chemicals and exposure to extreme temperatures. INCOMPATIBLE MATERIALS This product is not compatible with strong bases and strong acids. HAZARDOUS DECOMPOSITION PRODUCTS Thermal decomposition of this product can generate dusts, irritating fumes, and toxic gases (e.g., Carbon monoxide, Carbon dioxide). POSSIBILITY OF HAZARDOUS REACTIONS This product is not expected to undergo hazardous polymerization, decomposition, condensation or self-reactivity. 6. SPILL OR DISPOSAL PROCEDURES Steps to be taken in case material is released or spilled: For small spills, collect material and dispose per federal, state and local regulations. For larger spills (CERLA reportable quantity is 100lbs for unlisted hazardous waste), isolate area which may present a slip hazard. Sweep or collect material and dispose per federal, state and local regulations. Waste Disposal Method Dispose of container in compliance with all federal, state and local regulations. 7. SPECIAL PROTECTION INFORMATION Respiratory Protection: Not Required Ventilation: Not Required Protective Gloves: Recommended for use when handling the gel Eye Protection: Not Required 8. SPECIAL PRECAUTIONS Precautions to be taken in handling and storage: Avoid storage at elevated temperatures, prevent contamination and exposure to direct sunlight. 9. REGULATORY INFORMATION Not meant to be all inclusive-selected regulations represented Contents of this MSDS comply with OSHA Hazard Communication Standard 29 CFR 1910.1200 All chemical substances used in the manufacturing of this product comply with TSCA inventory reporting requirement; SARA and CERCLA chemical listings. NOTICE: The information and recommendations presented have been compiled from sources believed to be accurate and represent reliable and reasonable opinion on the subject when MSDS was prepared. No warranty, expressed or implied is intended. Each user should review these recommendations in the specific context of the intended use. ACRONYMS and ABBREVIATIONS: ACGIH - American Conferences of Governmental Industrial Hygienist CAS - Chemical Abstract Service registry number CERCLA - Comprehensive Emergency Response Compensation and Liability Act ND - Not Determined NK - Not Known PEL - Permissible Exposure Limit SARA - Superfund Ammendment Reauthorization Act TLV - Threshold Limit Value (registered trademark of ACGIH) TSCA - Toxic Substance Control Act