PRESTONE(R)

SECTION 2: Hazards identification

EMERGENCY OVERVIEW Eye and upper respiratory irritant. May cause nausea, vomiting, headache, drowsiness, blurred vision, convulsions, coma or death if ingested or inhaled. Prolonged or repeated skin contact may cause dermatitis or skin sensitization.

Potential health effects

INHALATION: May cause irritation of the nose and throat with headache, particularly from mists. High vapor concentrations caused, for example, by heating the material in an enclosed and poorly ventilated workplace, may produce nausea, vomiting, headache, dizziness and irregular eye movements. SKIN CONTACT: No evidence of adverse effects from available information. EYE CONTACT: Liquid, vapors or mist may cause discomfort in the eye with persistent conjunctivitis, seen as slight excess redness or conjunctiva. Serious corneal injury is not anticipated. INGESTION: May cause abdominal discomfort or pain, nausea, vomiting, dizziness, drowsiness, malaise, blurring of vision, irritability, back pain, decrease in urine output, kidney failure, and central nervous system effects, including irregular eye movements, convulsions and coma. Cardiac failure and pulmonary edema may develop. Severe kidney damage which may be fatal may follow the swallowing of ethylene glycol. A few reports have been published describing the development of weakness of the facial muscles, diminishing hearing, and difficulty with swallowing, during the late stages of severe poisoning.

Potential chronic health

Prolonged or repeated inhalation exposure may produce signs of central nervous system involvement, particularly dizziness and jerking eye movements. Prolonged or repeated skin contact may cause skin sensitization and an associated dermatitis in some individuals. Ethylene glycol has been found to cause birth defects in laboratory animals. The significance of this finding to humans has not been determined. See section 11 for additional information. MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE: The available toxicological information and a knowledge of the physical and chemical properties of the material suggest that overexposure in unlikely to aggravate existing medical conditions. CARCINOGEN: None of the components of these products is listed as a carcinogen or suspected carcinogen by IARC, NTP or OSHA. 4: