Nama Produk

SECTION 2: Hazards identification

1272/2008 Specific M-Factor registration Index No) according to concentration (long-term) number Regulation limit (SCL) (EC) No.

Hazard statements

see section 16 Acute Toxicity Estimate No information available Chemical name Oral LD50 mg/kg Dermal LD50 mg/kg Inhalation LC50 - 4 Inhalation LC50 - 4 Inhalation LC50 - 4 hour - dust/mist - hour - vapor - mg/L hour - gas - ppm mg/L HEPES 2000 No data available 7365-45-9 Triton X-100 1800 No data available 9002-93-1

Storage

Conditions Keep container tightly closed in a dry and well-ventilated place. 7.3. Specific end use(s) Metode Manajemen Risiko (RMM) Informasi yang diperlukan tercantum dalam Lembar Data Keselamatan ini. SECTION 8: Exposure controls/personal protection 8.1. Control parameters Exposure Limits This product, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region specific regulatory bodies. Biological occupational exposure This product, as supplied, does not contain any hazardous materials with biological limits limits established by the region specific regulatory bodies. Derived No Effect Level (DNEL) - Workers No information available Derived No Effect Level (DNEL) - General Public No information available. Predicted No Effect Concentration (PNEC) No information available. 8.2. Exposure controls Engineering controls No information available. Alat pelindung diri Eye/face protection Appropriate eye/face protection should be selected and used according to the chemical nature, hazards and use of this product and safety requirements of the local jurisdiction. Hand protection Appropriate hand protection should be selected and used according to the chemical nature, hazards and use of this product and safety requirements of the local jurisdiction. Skin and body protection Appropriate skin and body protection should be selected and used according to the chemical nature, hazards and use of this product and safety requirements of the local jurisdiction. Respiratory protection Appropriate respiratory protection should be selected and used according to the chemical nature, hazards and use of this product and safety requirements of the local jurisdiction. If exposure limits are exceeded or irritation is experienced, ventilation and evacuation may be required. General hygiene considerations Handle in accordance with good industrial hygiene and safety practice. Environmental exposure controls No information available. BAGIAN 9: Sifat fisika dan kimia 9.1. Information on basic physical and chemical properties Physical state Solid Penampakan endapan terliofilisasi Warna Putih hingga off-white Bau Tidak ada informasi yang tersedia. Ambang bau Tidak ada informasi yang tersedia Property Values

Remarks

Method Melting point / freezing point No data available Tak satu pun diketahui Initial boiling point and boiling No data available Tak satu pun diketahui range Kemudahan menyala No data available Tak satu pun diketahui Flammability Limit in Air Tak satu pun diketahui Upper flammability or explosive No data available limits Lower flammability or explosive No data available limits Titik nyala No data available Tak satu pun diketahui Suhu penyulutan otomatis No data available Tak satu pun diketahui Suhu dekomposisi Tak satu pun diketahui pH No data available Tidak berlaku pH (sebagai larutan berair) No data available None known Kekentalan kinematik No data available Tak satu pun diketahui Kekentalan dinamis No data available Tak satu pun diketahui Water solubility No data available Tak satu pun diketahui Kelarutan No data available Tak satu pun diketahui Koefisien partisi No data available Tak satu pun diketahui Tekanan uap No data available Tak satu pun diketahui Kerapatan relatif No data available Tidak berlaku Kerapatan curah No data available Liquid Density data tidak tersedia Relative vapor density No data available Tak satu pun diketahui Particle characteristics Particle Size Tidak ada informasi yang tersedia Particle Size Distribution Tidak ada informasi yang tersedia

Further information

9.2.1. Information with regard to physical hazard classes Tidak berlaku 9.2.2. Other safety characteristics Tidak ada informasi yang tersedia BAGIAN 10: Stabilitas dan reaktivitas 10.1. Reactivity Reactivity No information available. 10.2. Chemical stability Stability Stable under normal conditions. Data ledakan Sensitivity to mechanical impact None. Sensitivity to static discharge None. 10.3. Possibility of hazardous reactions Possibility of hazardous reactions None under normal processing. 10.4. Conditions to avoid Conditions to avoid None known based on information supplied. 10.5. Incompatible materials Incompatible materials None known based on information supplied. 10.6. Hazardous decomposition products Hazardous decomposition products Tidak ada yang diketahui berdasarkan informasi yang diberikan. BAGIAN 11: Informasi toksikologis 11.1. Information on hazard classes as defined in Regulation (EC) No 1272/2008 Information on likely routes of exposure Product Information Inhalation Specific test data for the substance or mixture is not available. Eye contact Specific test data for the substance or mixture is not available. Skin contact Specific test data for the substance or mixture is not available. Ingestion Specific test data for the substance or mixture is not available. Symptoms related to the physical, chemical and toxicological characteristics Symptoms No information available. Acute toxicity Numerical measures of toxicity No information available The following values are calculated based on chapter 3.1 of the GHS document ATEmix (oral) 13,529.00 mg/kg ATEmix (dermal) 43,197.00 mg/kg 0 % of the mixture consists of ingredient(s) of unknown acute oral toxicity. 0 % of the mixture consists of ingredient(s) of unknown acute dermal toxicity. 0 % of the mixture consists of ingredient(s) of unknown acute inhalation toxicity (gas). 0 % of the mixture consists of ingredient(s) of unknown acute inhalation toxicity (vapor). 0 % of the mixture consists of ingredient(s) of unknown acute inhalation toxicity (dust/mist). Chemical name Oral LD50 Dermal LD50 Inhalation LC50 HEPES > 2000 mg/kg ( Rat ) - Triton X-100 = 1800 mg/kg ( Rat ) - Efek tertunda dan seketika serta efek kronis akibat paparan jangka pendek dan jangka panjang Skin corrosion/irritation No information available. Serious eye damage/eye irritation No information available. Respiratory or skin sensitization No information available. Germ cell mutagenicity No information available. Carcinogenicity No information available. Reproductive toxicity No information available. STOT - single exposure No information available. STOT - repeated exposure No information available. Aspiration hazard No information available. 11.2. Information on other hazards 11.2.1. Endocrine disrupting properties Endocrine disrupting properties No information available. 11.2.2. Other information Efek merugikan lainnya Tidak ada informasi yang tersedia. BAGIAN 12: Informasi ekologis 12.1. Toxicity Ecotoxicity The environmental impact of this product has not been fully investigated. Unknown aquatic toxicity Contains 95.38 % of components with unknown hazards to the aquatic environment. Chemical name Algae/aquatic plants Fish Toxicity to Crustacea microorganisms HEPES - LC50: >100mg/L (96h, - Danio rerio) 12.2. Persistence and degradability Persistensi dan keteruraian Tidak ada informasi yang tersedia. 12.3. Bioaccumulative potential Bioaccumulation There is no data for this product. Chemical name Partition coefficient HEPES <-3.85 12.4. Mobility in soil Mobilitas di tanah Tidak ada informasi yang tersedia. 12.5. Results of PBT and vPvB assessment PBT and vPvB assessment The product does not contain any substance(s) classified as PBT or vPvB above the threshold of declaration. Chemical name PBT and vPvB assessment HEPES The substance is not PBT / vPvB 12.6. Endocrine disrupting properties Endocrine disrupting properties . 12.7. Other adverse effects Tidak ada informasi yang tersedia. SECTION 13: Disposal considerations 13.1. Waste treatment methods Waste from residues/unused Dispose of in accordance with local regulations. Dispose of waste in accordance with products environmental legislation. Contaminated packaging Do not reuse empty containers. BAGIAN 14: Informasi transportasi IATA 14.1 UN number or ID number Not regulated 14.2 14.3 Transport hazard class(es) Not regulated 14.4 Kelompok kemasan Tidak teregulasi 14.5 Bahaya lingkungan Tidak berlaku 14.6 Special precautions for user Ketentuan khusus Tidak ada IMDG 14.1 UN number or ID number Not regulated 14.2 14.3 Transport hazard class(es) Tidak teregulasi 14.4 Kelompok kemasan Tidak teregulasi 14.5 Bahaya lingkungan Tidak berlaku 14.6 Special precautions for user Ketentuan khusus Tidak ada 14.7 Maritime transport in bulk Tidak ada informasi yang tersedia according to IMO instruments RID 14.1 UN number or ID number Tidak teregulasi 14.2 14.3 Transport hazard class(es) Tidak teregulasi 14.4 Kelompok kemasan Tidak teregulasi 14.5 Bahaya lingkungan Tidak berlaku 14.6 Special precautions for user Ketentuan khusus Tidak ada ADR 14.1 UN number or ID number Tidak teregulasi 14.2 14.3 Transport hazard class(es) Tidak teregulasi 14.4 Kelompok kemasan Tidak teregulasi 14.5 Bahaya lingkungan Tidak berlaku 14.6 Special precautions for user Ketentuan khusus Tidak ada BAGIAN 15: Informasi terkait peraturan 15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture Uni Eropa Take note of Directive 98/24/EC on the protection of the health and safety of workers from the risks related to chemical agents at work. Authorizations and/or restrictions on use: This product contains one or more substance(s) subject to authorization (Regulation (EC) No. 1907/2006 (REACH), Annex XIV) This product contains one or more substance(s) subject to restriction (Regulation (EC) No. 1907/2006 (REACH), Annex XVII) Chemical name Restricted substance per REACH Substance subject to authorization per Annex XVII REACH Annex XIV Triton X-100 - 9002-93-1 - 42. Persistent Organic Pollutants Tidak berlaku Ozone-depleting substances (ODS) regulation (EC) 1005/2009 Tidak berlaku Inventarisasi Internasional TSCA Contact supplier for inventory compliance status DSL/NDSL Contact supplier for inventory compliance status EINECS/ELINCS Contact supplier for inventory compliance status ENCS Contact supplier for inventory compliance status IECSC Teregulasi KECL Contact supplier for inventory compliance status PICCS Contact supplier for inventory compliance status AIIC Contact supplier for inventory compliance status NZIoC Contact supplier for inventory compliance status Keterangan: TSCA - UU Pengendalian Zat Toksik Amerika Serikat Bagian 8(b) Inventarisasi DSL/NDSL - Daftar Zat Domestik/Daftar Zat Non-Domestik Kanada EINECS/ELINCS - Inventarisasi Zat Kimia Komersial yang Beredar di Eropa/Daftar Zat Kimia yang Diberitahukan di Eropa ENCS - Zat Kimia yang Sudah Ada dan Baru di Jepang IECSC - Inventarisasi Zat Kimia yang Sudah Ada di Cina KECL - Zat Kimia yang Sudah Ada dan Dievaluasi di Korea Selatan PICCS - Inventarisasi Bahan Kimia dan Zat Kimia Filipina AICS - Inventarisasi Bahan Kimia Australia (Australian Inventory of Chemical Substances) NZIoC - Inventarisasi Bahan Kimia Selandia Baru 15.2. Chemical safety assessment Laporan Keselamatan Bahan Kimia Tidak ada informasi yang tersedia BAGIAN 16: Informasi lainnya Kunci atau keterangan untuk singkatan dan akronim yang digunakan dalam lembar data keselamatan Keterangan SVHC: Substances of Very High Concern for Authorization: PBT: Persistent, Bioaccumulative, and Toxic (PBT) Substances vPvB: Very Persistent and very Bioaccumulative (vPvB) Substances STOT: Specific Target Organ Toxicity ATE: Acute Toxicity Estimate LC50: 50% Lethal Concentration LD50: 50% Lethal Dose Keterangan Section 8: Exposure controls/personal protection TWA TWA (rata-rata tertimbang waktu)