LOCTITE PC 6231 A known as

SECTION 2: Hazards identification

EMERGENCY OVERVIEW

Principle Routes of Exposure

Skin, Inhalation, Eyes, Ingestion, Aerosols or vapors can be formed during heating, foaming, or spraying.

Potential health effects

Inhalation Methylene bisphenyl isocyanate (MDI) vapors or mist at concentrations above the TLV can irritate the mucous membranes in the respiratory tract (nose, throat, lungs) causing runny nose, sore throat, coughing, chest discomfort, shortness of breath and reduced lung function (breathing obstruction). Persons with preexisting, nonspecific bronchial hyper-reactivity can respond to concentrations below the TLV with similar symptoms as well as lead to bronchitis, bronchial spasm and pulmonary edema (fluid in lungs). Chronic: As a result of previous repeated overexposures or a single large dose, certain individuals will develop isocyanate sensitization (chemical asthma) which will cause them to react to a later exposure to isocyanate at levels well below the TLV. Chronic overexposure to isocyanates has been reported to cause lung damage. These symptoms, which can include chest tightness, wheezing, cough, shortness of breath or asthma attack, could be immediate or delayed (up to several hours after exposure). Similar to many non-specific asthmatic responses, there are reports that once sensitized an individual can experience these symptoms upon exposure to dust, cold air, or other irritants. This increased lung sensitivity can persist for weeks and in severe cases for several years. Over exposure to isocyanates has also been reported to cause lung damage (including decrease in lung function) which may be permanent. Sensitization can either be temporary or permanent. Skin contact Isocyanates react with skin protein and moisture and can cause irritation which may include the following symptoms: reddening, swelling, rash, scaling or blistering. Cured material is difficult to remove. Chronic: Prolonged contact can cause reddening, swelling, rash, scaling, blistering and in some cases, skin sensitization. Individuals who have skin sensitization can develop these symptoms from contact with liquid or vapor. Animal tests have indicated that respiratory sensitization can result from skin contact with MDI. These data reinforce the need to prevent direct skin contact with MDI. Eye contact Liquid, aerosols or vapor are irritating and can cause tearing, reddening and swelling. If left untreated, corneal damage can occur and injury is slow to heal. Damage however is usually reversible. See Section 4 for First Aid measures. Ingestion Irritation and corrosive action can occur in the mouth, stomach tissue and digestive tract if swallowed. Symptoms can include sore throat, abdominal pain, nausea, vomiting and diarrhea. Existing conditions aggravated by Asthma. Other respiratory disorders (bronchitis, emphysema, bronchial hyperreactivity). Skin exposure allergies. Eczema. See Section 11 for additional toxicological information.