DIREX

SECTION 2: Hazards identification

---------------------------------------------------------------------- Emergency Overview Caution! Causes eye irritation. May irritate nose, throat and skin. Avoid breathing spray mist. Avoid contact with skin, eyes and clothing.

Potential health effects

Skin contact with Diuron may cause skin irritation with discomfort or rash. Significant skin permeation and systemic toxicity after contact appear unlikely. There are no reports of human sensitization. Eye contact with Diuron may cause eye irritation with discomfort, tearing, or blurring of vision. Based on data from animal testing, ingestion of large amounts may cause alterations in red blood cell counts and/or anemia, and spleen and liver effects. No adequate epidemiologic studies are available for this compound. The estimated lethal oral dose of Ethylene Glycol in humans is 100 mL. Immediate effects of inhalation overexposure to Ethylene Glycol may include irritation of the nose and throat with sneezing, sore throat or runny nose. Gross overexposure may cause pulmonary edema (body fluid in the lungs) with cough, wheezing, abnormal lung sounds, possibly progressing to severe shortness of breath and bluish discoloration of the skin; symptoms may be delayed. Skin contact with Ethylene Glycol may cause irritation with itching, burning, redness, swelling or rash. Skin permeation may occur in amounts capable of producing the effects of systemic toxicity. There are no reports of human sensitization. Eye contact with Ethylene Glycol may cause eye irritation with tearing, pain or blurred vision. Immediate effects of overexposure to Ethylene Glycol by inhalation or ingestion may include headache and nausea. Gross overexposure may cause central nervous system depression with dizziness, confusion, incoordination, drowsiness or unconsciousness; convulsions; altered kidney function which may be accompanied by abnormal urine volume, low back pain, discomfort or edema; kidney failure; deposits of calcium oxalate in the brain, spinal cord and kidneys; liver abnormalities; high blood pressure; irregular heart beat with a strange sensation in the chest, "heart thumping", apprehension, lightheadedness, feeling of fainting, dizziness, weakness, sometimes progressing to loss of consciousness and death. Other effects may include congestive heart failure; Continued) retention of acid in the blood, making oxygen less available in the blood stream and leading to symptoms of increased pulse rate, nausea, vomiting, confusion and weakness which may progress to loss of consciousness; low blood sugar; low blood calcium with muscle twitching; involuntary movement of the eyes; facial paralysis; or fatality. No increases in chromosomal changes were noted in the circulating blood of workers exposed to Ethylene Glycol. Increased susceptibility to the effects of Ethylene Glycol may be observed in persons with pre-existing disease of the kidneys. Carcinogenicity Information