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SECTION 2: Hazards identification

EMERGENCY OVERVIEW: This section not in use

Potential health effects

week CONTINUED ON NEXT PAGE *** PAGE: 002 INGESTION: May be harmful if swallowed. SKIN CONTACT: Uneured product contact will irritate lips, gums and tongue. Uncured product contact may irritate the skin. INHALATION: Causes irritation of the mouth, nose, and throat. Applies only in uncured state. EYE CONTACT: Uncured product contact irritates eyes.

Medical Conditions Generally Aggravated by Exposure

None known. SUBCHRONIC (TARGET ORGAN) EFFECTS: Reproductive disorders. May cause liver effects. CHRONIC EFFECTS/CARCINOGENICITY: This product or one of its ingredients present 0.1% or more is NOT listed as a carcinogen or suspected carcinogen by NTP, IARC,

Principle Routes of Exposure

Eyes. Inhalation. OTHER: Octamethyleyclotetrasiloxane Ingestion: Rodents given large doses via oral gavage of octamethyleyclotetrasiloxane (1600 mg/kg day, 14 days) developed increased liver weights relative to unexposed control animals due to hepatocellular hyperplasia (increased number of liver cells which appeared normal) as well as hypertrophy (increased cell size). Inhalation: In inhalation studies, laboratory rodents exposed to octamethylcyclotetrasiloxane (300 ppm five days week, 90 days) developed increased liver weights in female animals relative to unexposed control animals. When the exposure was stopped, liver weights returned to normal. Microscopic exami- nation of the liver cells did not show any evi- dence of pathology. Inhalation studies utilizing laboratory rabbits and guinea pigs showed no effects on liver weights. Inhalation exposures typical of industrial usage (5-10 ppm) showed no toxic effects in rodents. Range finding reproductive studies were conducted (whole body inhalation, 70 days prior to mating, through mating, gestation and lactation) xk CONTINUED ON NEXT PAGE *** PAGE: 003 with octamethylcyclotetrasiloxane (D4). Rats were exposed to 70 and 700 ppm. In the 700 ppm group, there was a statistically significant reduction in mean litter size and in implantation sites. No D4 related clinical signs were observed in the pups and no exposure related pathological findings were found. Interim results from a two generation reproductive study in rats exposed to 500 and 700 ppm D4 (whole body inhalation, 70 days prior to mating, through mating, gestation and lactation) resulted in a statically significant decrease in live mean litter size as well as extended periods of off- spring delivery (dystocia). These results were not abserved at the 70 and 300 ppm dosing levels. The relevance of these data to humans is unclear. Further studies are ongoing. In developmental toxicity studies, rats and rabbits were exposed to octamethylcyclotetrasiloxane at concentrations up to 700 ppm and 500 ppm respectively. No teratogenic effects (birth defects) were observed in either study. This product contains Methylpolysiloxanes which can generate Formaldehyde at approximately 300 degrees Fahrenheit (150’C) and above, in atmospheres which contain oxygen. Formaldehyde is a skin and respiratory sensitizer, eye and throat irritant, acute toxicant, and potential cancer hazard. An MSDS for Formaldehyde is available from GE Silicones. FIRST AID MEASURES INGESTION: Rinse mouth with water several times. SKIN: To clean from skin, remove completely with a dry cloth or paper towel, before washing with detergent and water. Get medical attention if irritation persists. INHALATION: Move person to fresh air. EYES: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes and get medical attention if irritation persists. #* CONTINUED ON NEXT PAGE *** PAGE: 004 NOTE TO PHYSICIAN: None known.