Vismodegib

Hazard statements (CLP)

H302, H315, H319, H335, H350, H360

Code

Statements

H302

Harmful if swallowed

SECTION 2: Hazards identification

Classification of the substance or mixture GHS-US classification Acute toxicity (oral), Category 4 H302 Harmful if swallowed. Skin corrosion/irritation, Category 2 H315 Causes skin irritation. Serious eye damage/eye irritation, Category 2 H319 Causes serious eye irritation. Carcinogenicity, Category 1A H350 May cause cancer. Reproductive toxicity, Category 1A H360 May damage fertility or the unborn child. Specific target organ toxicity – Single exposure, Category 3, H335 May cause respiratory irritation. Respiratory tract irritation Full text of H-statements: see section 16

2.2 Label elements

GHS US labelling

Signal word

Danger

Hazard statements

H302 - Harmful if swallowed H315 - Causes skin irritation H319 - Causes serious eye irritation H335 - May cause respiratory irritation H350 - May cause cancer. H360 - May damage fertility or the unborn child.

Precautionary statements

P201 - Obtain special instructions before use. P202 - Do not handle until all safety precautions have been read and understood. P261 - Avoid breathing dust, fume, gas, mist, vapours, spray. P264 - Wash hands, forearms and face thoroughly after handling. P270 - Do not eat, drink or smoke when using this product. P271 - Use only outdoors or in a well-ventilated area. P280 - Wear protective gloves. P301+P312 - If swallowed: Call a poison center or doctor if you feel unwell. P302+P352 - If on skin: Wash with plenty of water. P304+P340 - If inhaled: Remove person to fresh air and keep comfortable for breathing. P305+P351+P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308+P313 - If exposed or concerned: Get medical advice/attention. P312 - Call a poison center or doctor if you feel unwell. P321 - Specific treatment (see supplemental first aid instruction on this label). P330 - Rinse mouth. P332+P313 - If skin irritation occurs: Get medical advice or attention. P337+P313 - If eye irritation persists: Get medical advice or attention. P362+P364 - Take off contaminated clothing and wash it before reuse. P403+P233 - Store in a well-ventilated place. Keep container tightly closed. P405 - Store locked up. P501 - Dispose of contents and/or container to hazardous or special waste collection point, in accordance with local, regional, national and/or international regulations. 2.3. Hazards associated with known or reasonably anticipated uses No additional information available

2.3 Other hazards

No additional information available 2.5. Unknown acute toxicity No additional information available

2.1 Classification of the substance or mixture

GHS-US classification Acute toxicity (oral), Category 4 H302 Harmful if swallowed. Skin corrosion/irritation, Category 2 H315 Causes skin irritation. Serious eye damage/eye irritation, Category 2 H319 Causes serious eye irritation. Carcinogenicity, Category 1A H350 May cause cancer. Reproductive toxicity, Category 1A H360 May damage fertility or the unborn child. Specific target organ toxicity – Single exposure, Category 3, H335 May cause respiratory irritation. Respiratory tract irritation Full text of H-statements: see section 16 2.2. Label elements GHS US labelling Hazard pictograms (GHS US) : Signal word (GHS US) : Danger