Topotecan HCl

Hazard statements (CLP)

H300, H340, H350, H360, H412

Code

Statements

H300

Fatal if swallowed

SECTION 2: Hazards identification

Classification of the substance or mixture GHS-US classification Acute toxicity (oral), Category 2 H300 Fatal if swallowed. Germ cell mutagenicity, Category 1B H340 May cause genetic defects. Carcinogenicity, Category 1B H350 May cause cancer. Reproductive toxicity, Category 1B H360 May damage fertility or the unborn child. Hazardous to the aquatic environment — Chronic Hazard, Category 3 H412 Harmful to aquatic life with long lasting effects Full text of H-statements: see section 16

2.2 Label elements

GHS US labelling

Signal word

Danger

Hazard statements

H300 - Fatal if swallowed H340 - May cause genetic defects. H350 - May cause cancer. H360 - May damage fertility or the unborn child. H412 - Harmful to aquatic life with long lasting effects

Precautionary statements

P201 - Obtain special instructions before use. P202 - Do not handle until all safety precautions have been read and understood. P264 - Wash hands, forearms and face thoroughly after handling. P270 - Do not eat, drink or smoke when using this product. P273 - Avoid release to the environment. P280 - Wear protective gloves, protective clothing, eye protection, face protection, and hearing protection. P301+P310 - If swallowed: Immediately call a poison center or doctor. P308+P313 - If exposed or concerned: Get medical advice/attention. P321 - Specific treatment (see supplemental first aid instruction on this label). P330 - Rinse mouth. P405 - Store locked up. P501 - Dispose of contents and/or container to hazardous or special waste collection point, in accordance with local, regional, national and/or international regulations. 2.3. Hazards associated with known or reasonably anticipated uses No additional information available

2.3 Other hazards

No additional information available 2.5. Unknown acute toxicity No additional information available

2.1 Classification of the substance or mixture

GHS-US classification Acute toxicity (oral), Category 2 H300 Fatal if swallowed. Germ cell mutagenicity, Category 1B H340 May cause genetic defects. Carcinogenicity, Category 1B H350 May cause cancer. Reproductive toxicity, Category 1B H360 May damage fertility or the unborn child. Hazardous to the aquatic environment — Chronic Hazard, Category 3 H412 Harmful to aquatic life with long lasting effects. Full text of H-statements: see section 16 2.2. Label elements GHS US labelling Hazard pictograms (GHS US) : Signal word (GHS US) : Danger