Dabrafenib (GSK2118436)

Hazard statements (CLP)

H361, H373, H400, H411

Code

Statements

H361

Suspected of damaging fertility or the unborn child

SECTION 2: Hazards identification

Classification of the substance or mixture GHS-US classification Reproductive toxicity, Category 2 H361 Suspected of damaging fertility or the unborn child. Specific target organ toxicity — Repeated exposure, Category 2 H373 May cause damage to organs through prolonged or repeated exposure Hazardous to the aquatic environment — Acute Hazard, Category 1 H400 Very toxic to aquatic life. Hazardous to the aquatic environment — Chronic Hazard, Category 2 H411 Toxic to aquatic life with long lasting effects Full text of H-statements: see section 16

2.2 Label elements

GHS US labelling

Signal word

Warning

Hazard statements

H361 - Suspected of damaging fertility or the unborn child. H373 - May cause damage to organs through prolonged or repeated exposure H400 - Very toxic to aquatic life H411 - Toxic to aquatic life with long lasting effects

Precautionary statements

P201 - Obtain special instructions before use. P202 - Do not handle until all safety precautions have been read and understood. P260 - Do not breathe dust, fume, gas, mist, vapours, spray. P273 - Avoid release to the environment. P280 - Wear protective gloves, protective clothing, eye protection, face protection, and hearing protection. P308+P313 - If exposed or concerned: Get medical advice/attention. P314 - Get medical advice or attention if you feel unwell. P391 - Collect spillage. P405 - Store locked up. P501 - Dispose of contents and/or container to hazardous or special waste collection point, in accordance with local, regional, national and/or international regulations. 2.3. Hazards associated with known or reasonably anticipated uses No additional information available

2.3 Other hazards

No additional information available 2.5. Unknown acute toxicity No additional information available

2.1 Classification of the substance or mixture

GHS-US classification Reproductive toxicity, Category 2 H361 Suspected of damaging fertility or the unborn child. Specific target organ toxicity — Repeated exposure, Category 2 H373 May cause damage to organs through prolonged or repeated exposure. Hazardous to the aquatic environment — Acute Hazard, Category 1 H400 Very toxic to aquatic life. Hazardous to the aquatic environment — Chronic Hazard, Category 2 H411 Toxic to aquatic life with long lasting effects. Full text of H-statements: see section 16 2.2. Label elements GHS US labelling Hazard pictograms (GHS US) : Signal word (GHS US) : Warning