Crizotinib

Hazard statements (CLP)

H317, H319, H341, H400

Code

Statements

H317

May cause an allergic skin reaction

SECTION 2: Hazards identification

Classification of the substance or mixture GHS-US classification Serious eye damage/eye irritation, Category 2 H319 Causes serious eye irritation. Skin sensitization, Category 1 H317 May cause an allergic skin reaction. Germ cell mutagenicity, Category 2 H341 Suspected of causing genetic defects. Hazardous to the aquatic environment — Acute Hazard, Category 1 H400 Very toxic to aquatic life Full text of H-statements: see section 16

2.2 Label elements

GHS US labelling

Signal word

Warning

Hazard statements

H317 - May cause an allergic skin reaction H319 - Causes serious eye irritation H341 - Suspected of causing genetic defects. H400 - Very toxic to aquatic life

Precautionary statements

P201 - Obtain special instructions before use. P202 - Do not handle until all safety precautions have been read and understood. P261 - Avoid breathing dust, fume, gas, mist, vapours, spray. P264 - Wash hands, forearms and face thoroughly after handling. P272 - Contaminated work clothing must not be allowed out of the workplace. P273 - Avoid release to the environment. P280 - Wear protective gloves, protective clothing, eye protection, face protection, and hearing protection. P302+P352 - If on skin: Wash with plenty of water. P305+P351+P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308+P313 - If exposed or concerned: Get medical advice/attention. P321 - Specific treatment (see supplemental first aid instruction on this label). P333+P313 - If skin irritation or rash occurs: Get medical advice or attention. P337+P313 - If eye irritation persists: Get medical advice or attention. P362+P364 - Take off contaminated clothing and wash it before reuse. P391 - Collect spillage. P405 - Store locked up. P501 - Dispose of contents and/or container to hazardous or special waste collection point, in accordance with local, regional, national and/or international regulations. 2.3. Hazards associated with known or reasonably anticipated uses No additional information available

2.3 Other hazards

No additional information available 2.5. Unknown acute toxicity No additional information available

2.1 Classification of the substance or mixture

GHS-US classification Serious eye damage/eye irritation, Category 2 H319 Causes serious eye irritation. Skin sensitization, Category 1 H317 May cause an allergic skin reaction. Germ cell mutagenicity, Category 2 H341 Suspected of causing genetic defects. Hazardous to the aquatic environment — Acute Hazard, Category 1 H400 Very toxic to aquatic life. Full text of H-statements: see section 16 2.2. Label elements GHS US labelling Hazard pictograms (GHS US) : Signal word (GHS US) : Warning