General Information
Version
1.0
Revision date
2025-10-27
Product name
Adavosertib
Substance name
Adavosertib
Product Synonyms
MK-1775; AZD 1775
Chemical name
1,2-Dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)-phenyl]amino]-2-(2-propen-1-yl)-3H-pyrazolo[3,4-d]pyrimidin-3-one
CAS No.
955365-80-7
supplier name
G-Biosciences/ Geno Technology, Inc
Emergency telephone
1-800-424-9300, +1-703-527-3887
Icons in SDS
Company Information
company name
G-Biosciences/ Geno Technology, Inc
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H302, H340, H372
Hazard statements
Code
Statements
H302
Harmful if swallowed
Section 2
SECTION 2: Hazards identification
Classification of the substance or mixture GHS-US classification Acute toxicity (oral), Category 4 H302 Harmful if swallowed. Germ cell mutagenicity, Category 1B H340 May cause genetic defects. Specific target organ toxicity — Repeated exposure, Category 1 H372 Causes damage to organs through prolonged or repeated exposure Full text of H-statements: see section 16
2.2 Label elements
GHS US labelling
Signal word
Danger
Hazard statements
H302 - Harmful if swallowed H340 - May cause genetic defects. H372 - Causes damage to organs through prolonged or repeated exposure
Precautionary statements
P201 - Obtain special instructions before use. P202 - Do not handle until all safety precautions have been read and understood. P260 - Do not breathe dust, fume, gas, mist, vapours, spray. P264 - Wash hands, forearms and face thoroughly after handling. P270 - Do not eat, drink or smoke when using this product. P280 - Wear protective gloves, protective clothing, eye protection, face protection, and hearing protection. P301+P312 - If swallowed: Call a poison center or doctor if you feel unwell. P308+P313 - If exposed or concerned: Get medical advice/attention. P314 - Get medical advice or attention if you feel unwell. P330 - Rinse mouth. P405 - Store locked up. P501 - Dispose of contents and/or container to hazardous or special waste collection point, in accordance with local, regional, national and/or international regulations. 2.3. Hazards associated with known or reasonably anticipated uses No additional information available
2.3 Other hazards
No additional information available 2.5. Unknown acute toxicity No additional information available
2.1 Classification of the substance or mixture
GHS-US classification Acute toxicity (oral), Category 4 H302 Harmful if swallowed. Germ cell mutagenicity, Category 1B H340 May cause genetic defects. Specific target organ toxicity — Repeated exposure, Category 1 H372 Causes damage to organs through prolonged or repeated exposure. Full text of H-statements: see section 16 2.2. Label elements GHS US labelling Hazard pictograms (GHS US) : Signal word (GHS US) : Danger
