Mannitol Injection, USP

SECTION 2: Hazards identification

GHS Class: Reproductive toxicity. Effects on or via lactation.

Hazard statements

May cause harm to breast-fed children.

Precautionary statements

Obtain special instructions before use. Do not breathe dust/fume/gas/mist/vapours/spray. Avoid contact during pregnancy and while nursing. Wash hands thoroughly after handling. Do not eat, drink or smoke when using this product. IF exposed or concerned: Get medical advice/attention. Emergency Overview: This product is intended for therapeutic use only when prescribed by a physician. Potential adverse reactions from prescribed doses and overdoses are described in the package insert.

Principle Routes of Exposure

Inhalation Ingestion Eye contact Skin Absorption. Injection.

Potential health effects

Eye: Contact with eyes may cause irritation. Skin: May cause skin irritation. Inhalation: May cause irritation of respiratory tract. Ingestion: May cause irritation. Signs/Symptoms: Adverse reactions from therapeutic doses include: fluid and electrolyte imbalance, acidosis, dehydration, dryness of mouth, nausea, vomiting, diarrhea, osmotic nephrosis, urinary retention, headache, convulsions, dizziness, blurred vision, rhinitis, pulmonary edema, edema, hypotension, hypertension, tachycardia, angina-like chest pains, skin necrosis, thrombophlebitis, urticaria, thirst, arm pain, chills, and fever. Occupational exposure has not been fully investigated. Aggravation of Pre-Existing Individuals with well established anuria due to renal disease, severe pulmonary congestion or frank Conditions: pulmonary edema, active intracranial bleeding, severe dehydration, progressive renal damage or dysfunction, or progressive heart failure.