Ketorolac Tromethamine Injection, USP

Hazard statements (CLP)

H225, H315, H317, H318, H334, H362

Code

Statements

H225

Highly Flammable liquid and vapour

Signal word

DANGER. GHS Class Flammable Liquid. Category 2. Serious Eye Damage. category 1. Respiratory sensitisation. category 1. Skin Irritation. Category 2. Skin Sensitization. category 1. Reproductive toxicity. Effects on or via lactation.

Hazard statements

Highly flammable liquid and vapor. Causes serious eye damage. May cause allergy or asthma symptoms or breathing difficulties if inhaled. Causes skin irritation. May cause an allergic skin reaction. May cause harm to breast-fed children.

Precautionary statements

Obtain special instructions before use. Keep away from heat/sparks/open flames/hotsurfaces. — No smoking. Keep container tightly closed. Ground/Bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Do not breathe dust/fume/gas/mist/vapours/spray. Avoid breathing dust/fume/gas/mist/vapours/spray. Avoid contact during pregnancy and while nursing. Wash hands thoroughly after handling. Do not eat, drink or smoke when using this product. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. In case of inadequate ventilation wear respiratory protection. IF ON SKIN: Wash with plenty of water. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. Immediately call a POISON CENTER or doctor/physician. Specific treatment (see ... on this label). If skin irritation occurs: Get medical advice/attention. If skin irritation or rash occurs: Get medical advice/attention. If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Take off contaminated clothing and wash it before reuse. In case of fire: Use dry chemical, carbon dioxide to extinguish small fires. Use water for large fires. Store in a well-ventilated place. Keep cool. Dispose of contents/container in accordance with Local, State, Federal and Provincial regulations. Emergency Overview This product is intended for therapeutic use only when prescribed by a physician. Potential adverse reactions from prescribed doses and overdoses are described in the package insert.

Principle Routes of Exposure

Inhalation Ingestion Eye contact Skin Absorption. Injection.

Potential health effects

Eye Contact with eyes may cause irritation. Signs/Symptoms Adverse reactions from therapeutic doses include: edema, hypertension, pruritus, rash, nausea, dyspepsia, gastrointestinal pain, diarrhea, constipation, flatulence, gastrointestinal fullness, vomiting, stomatitis, purpura, headache, drowsiness, dizziness, and sweating. Occupational exposure has not been fully investigated. Aggravation of Pre-Existing Individuals with active peptic ulcer disease, gastrointestinal bleeding or perforation, history of peptic Conditions ulcer diseases, gastrointestinal bleeding, advanced renal impairment or at risk for renal failure due to volume depletion, hypersensitivity to ketorolac tromethamine, allergic manifestations to aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs), and those with medical conditions that are at high risk for bleeding.