Formerly known as an MSDS, or Material Safety Data Sheet, these documents provide important

SECTION 2: Hazards identification

GHS classification of the substance/mixture and any national or regional information

2.2 Label elements

(Hazard symbols may be by pictogram or by the name of the pictogram e.g. “flame”, “skull and crossbones”); • Other hazards which do not result in the classification (e.g. “dust explosion hazard”) or are not covered by the GHS. 2

2.1 Classification of the substance or mixture

• GHS label elements, including precautionary statements. (Hazard symbols may be by pictogram or by the name of the pictogram e.g. “flame”, “skull and crossbones”); • Other hazards which do not result in the classification (e.g. “dust explosion hazard”) or are not covered by the GHS. 2 3. Composition/information on ingredients: Substance • Chemical identity; • Common name, synonyms, etc.; • CAS number and other unique identifiers • Impurities and stabilizing additives which are themselves classified and which contribute to the classification of a substance. Mixture • The chemical identity and concentration or concentration ranges of all ingredients. 4. First aid measures • Description of necessary measures, subdivided according to the different routes of exposure, i.e. inhalation, skin and eye contact and ingestion; • Most important symptoms/effects, acute and delayed. • Indication of immediate medical attention and special treatment needed, if necessary. 5. Fire-fighting measures • Suitable (and unsuitable) extinguishing media. • Specific hazards arising from the chemical (e.g. nature of hazardous combustion products). • Special protective equipment and precautions for fire-fighters. 6. Accidental release measures • Personal precautions, protective equipment and emergency procedures. • Environmental precautions. • Methods and materials for containment and cleaning up. 7. Handling and storage • Precautions for safe handling. • Conditions for safe storage, including any incompatibilities. 8. Exposure controls/personal protection • Control parameters e.g. occupational exposure limit values or biological limit values. • Appropriate engineering controls. • Individual protection measures, such as personal protective equipment. 9. Physical and chemical properties • Appearance (physical state, color etc.); Odor; Odor threshold; pH; Melting point/freezing point; Initial boiling point and boiling range; Flash point; Evaporation rate; Flammability (solid, gas); Upper/lower flammability or explosive limits; Vapor pressure; Vapor density; Relative density; Solubility; Auto-ignition temperature; Decomposition temperature; Viscosity. 10. Stability and reactivity • Reactivity; • Chemical stability; • Possibility of hazardous reactions; • Conditions to avoid (e.g. static discharge, shock or vibration); • Incompatible materials; • Hazardous decomposition products. 3 11. Toxicological information • Information on the likely routes of exposure (inhalation, ingestion, skin and eye contact); • Symptoms related to the physical, chemical and toxicological characteristics; • Delayed and immediate effects and also chronic effects from short and long term exposure; • Numerical measures of toxicity (such as acute toxicity estimates). 12. Ecological information • Ecotoxicity (aquatic and terrestrial, where available); • Persistence and degradability; • Bioaccumulative potential; • Mobility in the soil; 13. Disposal information Description of waste residues and information on their safe handling and methods of disposal, including the disposal of any contaminated packaging. 14. Transport information • UN number; • UN proper shipping name: • Transport hazard class / classes; • Packing group, if applicable • Environmental hazards (e.g.: Marine pollutant (Yes/No)); • Transport in bulk (according to Annex II of MARPOL 73/78 and the IBC Code); • Special precautions which a user needs to be aware of, or needs to comply with, in connection with the transport or conveyance within or outside their premises. 15. Regulatory information Safety, health and environmental regulations specific for the product in question. 16. Other information including information on preparation and revision of the SDS A comprehensive file of Safety Data Sheets (SDS) must be kept on file in the laboratory / work area and be readily accessible to all employees during all work shifts. SDSs can be made available to employees via the Internet, but all personnel in the workplace must have access to a computer and be trained on how to access the correct SDS information. Helpful SDS search web sites are included in Appendix B. All departments/entities are required to maintain SDS information for their programs and ensure information is updated regularly, and that SDSs for materials no longer in use are maintained for 30 years. Laboratory workers should always READ and HEED the label and the Safety Data Sheet before using a chemical for the first time. Know the types of PPE that you will be required to wear when handling the chemical. Ensure that the ventilation in the laboratory will be adequate for your needs. Be familiar with the departmental and lab Chemical Hygiene Plan and Emergency Action Plan in the event of a chemical spill, fire, or explosion. 4 Section 5. NFPA Classification System In the event of an emergency in a laboratory, the National Fire Protection Association (NFPA) 704 “fire diamond” is designed to provide information to emergency responders regarding the chemical contents of a laboratory. The fire diamond provides information on the degree of danger for health hazards, fire hazards, and instability hazards. This information is also useful for personnel working in or around laboratories that have hazardous materials. The NFPA fire diamond is commonly displayed on chemical labels, secondary container labeling in the academic laboratories, and on the SDS. Additionally, it must be posted on entrance door(s) to each laboratory or area where hazardous materials are present. When posted on the laboratory door, the numerical ratings refer to the contents of the entire laboratory, not to a specific chemical within the laboratory. It is useful to conduct a chemical inventory to identify the hazards of all chemicals present and fill in the NFPA 704 diamond with this information, using the highest rating in each block from all of the chemicals present. NFPA 704: Standard System for the Identification of the Hazards of Materials for Emergency Response, 2012 Edition BLUE - HEALTH HAZARD 4 - Very short exposure can be lethal or cause major permanent injury 3 - Short exposure can cause serious temporary or moderate permanent injury 2 - Can cause temporary incapacitation or residual injury 1 - Can cause significant irritation 3 0 - Poses no health hazard, no precautions necessary RED - FLAMMABILITY HAZARD 4 2 4 - Will rapidly vaporize, or is readily dispersed in air, and will readily burn; flash point below 73 oF 3 - Can be ignited under almost all ambient temperature conditions; OX flash point between 73 oF and 100 oF 2 - Must be moderately heated or exposed to high ambient temperatures; W flash point between 100 oF and 200 oF 1 - Must be heated before ignition can occur; flash point over 200 oF 0 - Materials that will not burn YELLOW - INSTABLITY HAZARD 4 - Readily capable of detonation or explosive decomposition at normal temperatures and pressures 3 - Capable of detonation or explosive decomposition but must be heated; reacts explosively with water, or will detonate if severely shocked 2 - Readily undergoes violent chemical change at elevated temperatures and pressures; reacts violently