G4020 ANTI-GRAFFITI CLEAR (Part B)

SECTION 2: Hazards identification

OSHA HMIS HEALTH 2 * FLAMMABILITY 3 REACTIVITY 0 0 = Least 1 = Slight 2 = Moderate 3 = High 4 = Extreme

Potential chronic health

Routes of Entry: Eye contact, Inhalation, Skin contact, Absorption, Ingestion.

Medical Conditions Generally Aggravated by Exposure

Eye disease, Skin disease including eczema and sensitization, Kidney disease, Liver disease, Digestive tract disease, Lung disease. Immediate (Acute) Health Effects: Inhalation: Can cause moderate respiratory irritation, dizziness, weakness, fatigue, nausea and headache. Vapors or mist of Hexamethylene Diisocyanate (HDI) or polyisocyantates can irritate mucous membranes in the respiratory tract causing runny nose, sore throat, coughing, chest discomfort, shortness of breath and obstruct breathing. Susceptible individuals with preexisting bronchial hyperreactivity may exhibit similar symptoms at low concentrations in addition to an asthma attack. High exposure may lead to bronchitis, bronchial spasm and pulmonary edema (fluid in lungs). Chemical or hypersensitive pneumonitis (flu-like symptoms, including fever and chills) is possible. These effects are usually reversible. Skin Contact: HDI and polyisocyanates can cause skin irritation with symptoms such as reddening, swelling, rash, scaling and blistering. Skin sensitization is possible in some individuals. Cured HDI is difficult to remove. Can cause moderate skin irritation, defatting, and dermatitis. Not likely to cause permanent damage. Eye Contact: Can cause severe irritation. Eye contact may result in corneal injury. Symptoms may include discomfort or pain, excess blinking and tear production, with marked redness and swelling of the conjunctiva. Temporary vision impairment (cloudy or blurred vision) is possible. Irritating but will not permanently injure eye tissue. Skin Absorption: May cause irritation and minor systemic damage. Can be absorbed through the skin but exposure must be extensive before adverse health effects occur. Ingestion: May be slightly toxic by ingestion. Can cause abdominal discomfort, nausea, vomiting and diarrhea. Target Organ Acute Toxicity: Eyes, Skin, CNS, Respiratory System, PNS, Kidneys, Liver, Blood, Digestive Tract, Thyroid, Pituitary, Testes. Long-Term (Chronic) Health Effects: Inhalation: Upon prolonged and/or repeated exposure, can cause moderate respiratory irritation, dizziness, weakness, fatigue, nausea and headache. Overexposure to isocyanates like HDI and polyisocyanates can induce isocyanate sensitization (chemical asthma). Individuals with this condition will react to an isocyanate exposure at levels well below acceptable exposure limits. Symptoms such as chest tightness, wheezing, cough, shortness of breath or asthmatic attack could be immediate or delayed up to several hours after exposure. Dust, cold air or other irritants can trigger symptoms in sensitized individuals. This can persist for weeks and in severe cases for several years. Chronic overexposure to isocyanates can cause physiological changes in the lungs and a decrease in lung function. Lung damage may be permanent. Pulmonary sensitization may be either temporary or permanent. Prolonged or repeated inhalation may cause lung damage. Skin Contact: Upon prolonged or repeated contact, can cause moderate skin irritation, defatting, and dermatitis. Not likely to cause permanent damage. Prolonged contact with HDI or polyisocyanates can cause symptoms similar to acute skin exposure (see above). In skin sensitized individuals symptoms can develop after contact with very small amounts or even as a result of vapor-only exposure. Eye Contact: Upon prolonged or repeated contact, can cause severe irritation. Eye contact may result in corneal injury. Symptoms may include discomfort or pain, excess blinking and tear production, with marked redness and swelling of the conjunctiva. Temporary vision impairment (cloudy or blurred vision) is possible. Skin Absorption Upon prolonged or repeated exposure, harmful if absorbed through the skin. May cause severe irritation and systemic damage. Carcinogenicity: IARC: Yes NTP: No OSHA: No Target Organ Chronic Toxicity: Eyes, Skin, CNS, Respiratory System, PNS, Kidneys, Liver, Blood, Digestive Tract, Pituitary, Testes. NOTICE - Reports have associated repeated and prolonged occupational overexposure to solvents with brain and nervous system damage. Intentional misuse by deliberately concentrating and inhaling the contents may be harmful or fatal. Lifetime inhalation exposure of rats and mice to high concentrations of ethylbenzene (750 ppm) resulted in increases in certain types of cancer, including kidney, lung and liver tumors. Testicular adenomas were increased as were thyroid effects in rats at 750 ppm. Pituitary effects were observed in female mice at 250 ppm. These effects were absent when exposure was below 75 ppm ethylbenzene. The study does not address the relevance of these results to humans. IV. FIRST AID Inhalation: Remove to fresh air. If breathing is difficult, have a trained individual administer oxygen. If not breathing, give artificial respiration and have a trained individual administer oxygen. Get medical attention immediately.