Hematoxylin Stain Solution (Gill Formulation 2)

SECTION 2: Hazards identification

EMERGENCY OVERVIEW Appearance: not available liquid. Warning! Causes eye, skin, and respiratory tract irritation. May be harmful if swallowed or absorbed through the skin. May cause central nervous system effects. May cause kidney damage. Target Organs: Kidneys, central nervous system, eyes, skin, mucous membranes.

Potential health effects

Eye: Causes eye irritation. May cause chemical conjunctivitis. Skin: Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May be harmful if absorbed through the skin. Contact with the skin may cause blackening and hyperkeratosis of the skin of the hands. Ingestion: May cause systemic toxicity with acidosis. May cause liver and kidney damage. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. Ingestion produces toxicity which follows a 3 step progression. Stage 1 involves the central nervous system producing eye muscle paralysis, convulsions, and coma. Metabolic acidosis and swelling may occur. Stage 2 involves the cardiopulmonary system which may cause high blood pressure, rapid heart beat, and possible cardiac failure. Stage 3 results in kidney damage. Rapidly absorbed from the gastrointestinal tract. Causes digestive tract irritation. Inhalation: Causes respiratory tract irritation. May cause effects similar to those described for ingestion. Exposure may lead to bronchitis, pharyngitis, and dental erosion. May be absorbed through the lungs. Chronic: May cause kidney injury. Acetic acid can cause occupational asthma. One case of a delayed asthmatic response to glacial acetic acid has been reported in a person with bronchial asthma. Skin sensitization to acetic acid is rare, but has occurred. Repeated excessive exposure to ethylene glycol may cause irritation of the upper respiratory tract. In humans, effects have been reported on the central nervous system, including nystagmus (involuntary, rapid, rhythmic movement of the eyeball).